June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Characterization of Funding Sources in Ophthalmology Research
Author Affiliations & Notes
  • Sydney DeVore
    Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
  • Amrish Selvam
    Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
  • Rajan Alagar
    Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
  • Selina Chang
    Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
  • Amy Yu
    Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
  • Jay Chhablani
    Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   Sydney DeVore None; Amrish Selvam None; Rajan Alagar None; Selina Chang None; Amy Yu None; Jay Chhablani Salutaris, Allergan, Novartis, Erasca, Code C (Consultant/Contractor)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 5374. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Sydney DeVore, Amrish Selvam, Rajan Alagar, Selina Chang, Amy Yu, Jay Chhablani; Characterization of Funding Sources in Ophthalmology Research. Invest. Ophthalmol. Vis. Sci. 2023;64(8):5374.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose :
Industry-funded research has provided new opportunities for clinicians to obtain much-needed funding. However, such collaborations may introduce potential biases. In this study, we analyze the funding sources of published ophthalmic research in 2022 to understand the current distribution of funding across different study types.

Methods :
This was a cross-sectional study of publications from five reputable ophthalmology journals including Ophthalmology, JAMA Ophthalmology, American Journal of Ophthalmology (AJO), British Journal of Ophthalmology (BJO), and Investigative Ophthalmology and Visual Science (IOVS). All original articles published in the year 2022 were included. Exclusion criteria were systemic analyses, literature reviews, and case reports. The primary outcomes collected were the sources of funding and study design. Sources of funding were categorized as government, foundation, intramural, and industry. Chi-square testing was performed to analyze the categorical values using Stata16 (StataCorp, Texas USA).

Results :
A total of 1,073 articles were identified of which 98 (9.1%), 102 (9.5%), 293 (27.3%), 249 (23.2%), and 331 (30.8%) were published in Ophthalmology, JAMA Ophthalmology, AJO, BJO, and IOVS respectively. 168 (15.7%), 812 (75.7%), and 93 (8.7%) of the articles were basic science, observational, and interventional studies respectively. All basic science studies were published in IOVS. 655 (61.0%), 443 (41.3%), 228 (21.2%), and 124 (11.6%) of the studies received government, foundation, intramural, and industry funding respectively. Government funding was more frequently seen in basic science studies (86.3%, p < 0.001), while industry funding was more frequently seen in interventional studies (48.4%, p < 0.001). Other sources of funding were evenly distributed among study designs. Funding sources were not reported in 217 (20.2%) of the analyzed studies, which occurred more often in observational studies (24.1%, p < 0.001) as well as in AJO (31.1%) and BJO (32.9%, p < 0.001).

Conclusions : Industry funding supports a minority of the total published research but a significant proportion of the high-impact interventional studies such as randomized controlled trials. Transparent reporting of funding sources will be critical in upholding research integrity within the current landscape. A study analyzing longitudinal trends in funding sources is underway.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×