Abstract
Purpose :
To evaluate the DRI OCT Triton’s repeatability and reproducibility.
Methods :
Eligible subjects with normal eyes, glaucomatous eyes, and retina disease eyes were enrolled. Three DRI OCT Triton were employed. Each operator was specifically paired with one device to create three distinct operator/device configurations. Subjects were randomized to select the study eye and the testing order of the operator/device. The scan modes included the Triton- 3D Wide (12mmx9mm), 3D Macula (7mmx7mm), and 3D Disc (6mmx6mm). At least 3 scans were taken for each scan mode and each operator/device configuration. The following measurements were assessed: thickness of full retina in nine regions from the Early Treatment of Diabetic Retinopathy Study (ETDRS), ganglion cell complex (GCC / GCL++), ganglion cell layer (GCL) with inner plexiform layer (IPL)(GCL+), circumpapillary retinal nerve fiber layer (cpRNFL), as well as measurements of the optic disc such as cup to disc (C/D) ratio and rim area. All images were sent to the Topcon Reading Center for evaluation of image acceptance and quality grading. A two-way random-effect analysis of variance (ANOVA) model was used to estimate the repeatability and reproducibility limits of each parameter by subject population. The ANOVA model included the operator/device, eye, and interaction between operator/device and eye as the variance components. The variance components, repeatability and reproducibility limits, and coefficient of variation in percentage (CV%) were produced for each scan parameter by subject population.
Results :
25 normal eyes, 26 eyes with retinal disease, and 25 glaucoma eyes were tested. Image quality of B scans were mostly deemed good or excellent. Overall, the precision estimates (reproducibility limit, reproducibility CV%, repeatability limit and repeatability CV%) were relatively low indicating high precision, with most reproducibility limit better than 5 microns for most retinal parameters (See table for results for full retinal thickness measurements).
Conclusions :
The repeatability and reproducibility of the measurements demonstrated good precision for the DRI OCT Triton. The repeatability of the 7mmx7mm Macular scan was only slightly better than the 12mmx9mm Wide scan.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.