Abstract
Purpose :
To investigate the clinical outcomes of ab-interno canaloplasty (ABiC) with iTrack (Nova Eye Medical) as a standalone procedure or combined with gonioscopy-assisted transluminal trabeculotomy (GATT) over a 12-month period across all glaucoma severities and particularly in eyes with severe glaucoma.
Methods :
This was a non-randomized, single center, retrospective case series of adult patients, mostly with primary open-angle glaucoma, across all glaucoma severities, who were treated with either ABiC or ABiC+GATT with or without concomitant cataract surgery. Patients were stratified according to the procedure and then according to the severity of glaucoma.
Results :
47 eyes were included (mean age 59.3±16.5; 30 males and 17 females) in this study. The majority of the eyes (62%) had severe glaucoma. The overall mean baseline intraocular pressure (IOP) was 21.4±10.5 and it reduced to 14.5±8.2 and 13.6±5.5 (p<.001), while the mean baseline number of medications was 3.0±1.4 and was reduced to 1.9±1.3 and 1.7±1.5 (p<.001) at 3 and 6 months postoperatively, respectively. The mean ABiC cannulation degree was 306° (of the total 360°) and the mean GATT degree was 318°. Mean outcomes at baseline, 3 months and 6 months for the respective procedure groups are reported in table 1 for all eyes and in the table 2 for eyes categorized as severe glaucoma. Four eyes (8%) had additional glaucoma surgery (1 diode cyclophotocoagulation, 3 Baerveldt implant). No serious complications were observed but a choroidal detachment related to sequential aqueous shunt surgery occurred at post-operative month 4 in one case.
Conclusions :
ABiC and GATT, combined or not with cataract surgery resulted in a general reduction in IOP and number of glaucoma medications used.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.