Abstract
Purpose :
The purpose of this investigation is to evaluate the efficacy of several retinal imaging modalities, including (OCT) Optical coherence tomography, color fundus retinal photography, fluorescein angiography, and fundus photography, in detecting Age-Related Macular Degeneration.
Methods :
The PubMed database was reviewed for literature pertaining to the use of imaging technology in the detection of AMD. The exact search phrases "AMD and OCT," "AMD and Optos," and "AMD and Ultrasound" were applied to all time periods. This resulted in a total of 83 publications, of which 83 were unique and not duplicates, 33 had full texts available, 28 were topically relevant, and only 24 satisfied our evaluation's analysis standards. The information acquired from these 24 investigations included the imaging technologies utilized, the vascular and non-vascular ocular illnesses identified in patients, the patients' previous medical histories, and the sample size. Studies without sufficient data to overlap with at least two of these categories were excluded. This action was taken to eliminate any personal bias. In Figure 1, the authors of this research present a more comprehensive illustration of the filtration process.
Results :
Comparing the number of symptoms detected by OCT to the number of symptoms discovered when OCT was employed in conjunction with other imaging technologies, a significant difference was found (p-value = 0.0395, t-value = 2.1960). These figures were derived through a statistical analysis conducted on data collected from various studies included in this investigation. This suggests that combining OCT with other imaging technologies will result in improved illness diagnosis and, ultimately, treatment.
Conclusions :
Age-related macular degeneration is diagnosed by examining the retina's pathology. This study evaluates OCT and other imaging modalities for detecting vascular and non-vascular ocular abnormalities from AMD. Statistical analysis was conducted using data collected from multiple studies on Pubmed. Combining OCT and other imaging technologies enhanced macular degeneration detection. This shows that multiple imaging modalities are required to diagnose AMD accurately. Due to data and method constraints, further research is needed to confirm these conclusions.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.