Abstract
Purpose :
To investigate the risk factor in patients with focal choroidal excavation (FCE) and its correlation with chorioretinal diseases.
Methods :
Patients with FCE in Guangzhou Aier Eye Hospital from August 2016 to August 2022 were included in the study, and age- and gender-matched healthy subjects were enrolled for control. Demographics, clinical features, and multimode images were collected. Parameters of FCE on spectral-domain optical coherence tomography (SD-OCT) were manually measured by the built-in software and analyzed statistically.
Results :
Twenty-one patients (13/8, male/female) with FCE were included in this study. The age of the patients was 45.2±12.6 years, and the best-corrected visual acuity was 0.4±0.4 (LogMAR). FCE was present in 28 eyes of 21 patients, including independent FCE (12 eyes) and concurrent FCE (16 eyes) with choroidal neovascularization, central serous chorioretinopathy, et al. The age of concurrent FCE patients was significantly older than that of independent FCE (47.4±11.9 vs 34±8.0, p=0.015). The subfoveal choroidal thickness of the healthy subjects was significantly less than the fellow eyes of FCE patients (213.4±45μm vs 275.9±116.3μm, P<0.01), as well as the independent FCE (333.4±134.8μm, P<0.001) and concurrent FCE (293.7±102μm, P<0.001). The width of excavation was wider in concurrent FCE than independent FCE (1109.7±906.0μm vs 440.4±264.2μm, p=0.001).
Conclusions :
FCE may come from a congenital choroidal malformation or acquired. The width of excavation is a significant indicator in evaluating the risk of concurrent macular pathology. Chorioretinal disorders and FCE were mutually affected and fostered.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.