June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Assessment of scleral fixated intraocular lens tilt using extended depth OCT
Author Affiliations & Notes
  • Ngoc Lan Vy Truong
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • James Lai
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Katherine Krishna
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Brandon Chou
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Justin Chen
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Kyle Rowley
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
  • Pakravan Parastou
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Viet Chau
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Fabrice Manns
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Justin H. Townsend
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Marco Ruggeri
    Ophthalmic Biophysics Center, University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States
  • Footnotes
    Commercial Relationships   Ngoc Lan Vy Truong None; James Lai None; Katherine Krishna None; Brandon Chou None; Justin Chen None; Kyle Rowley None; Pakravan Parastou None; Viet Chau None; Fabrice Manns US8425037B2, Code P (Patent); Justin Townsend None; Marco Ruggeri US8425037B2, Code P (Patent)
  • Footnotes
    Support  National Eye Institute Grants 2R01EY14225, P30EY14801 (Center Grant), 1F30EY027162; Florida Lions Eye Bank; Drs KR Olsen and ME Hildebrandt, Drs R Urs and A Furtado; the Henri and Flore Lesieur Foundation (JMP)
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 5419. doi:
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    • Get Citation

      Ngoc Lan Vy Truong, James Lai, Katherine Krishna, Brandon Chou, Justin Chen, Kyle Rowley, Pakravan Parastou, Viet Chau, Fabrice Manns, Justin H. Townsend, Marco Ruggeri; Assessment of scleral fixated intraocular lens tilt using extended depth OCT. Invest. Ophthalmol. Vis. Sci. 2023;64(8):5419.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : One of the challenges of sutureless scleral fixation IOL implantation is to minimize tilt and decentration. The goal of the study is to develop an approach to assess IOL tilt and guide IOL placement using OCT, providing information on optical performance after scleral IOL fixation.

Methods : Following an IRB-approved protocol, extended-depth OCT images were acquired in four aphakic patients who underwent secondary implantation of a scleral fixated aspheric 3-piece IOL (CT LUCIA 602, Zeiss) using the Yamane technique. A custom-built extended-depth OCT system (Ruggeri et al, 2012) was used to image the entire anterior segment including the cornea and IOL. For each subject, we acquired a series of 72 radial OCT scans spaced 2.5 apart. The anterior and posterior surface of the cornea and the IOL were segmented in each image and the 3D shape of the 4 surfaces was reconstructed. All surfaces were motion corrected and fitted with third order polynomial functions and then corrected for distortion due to refraction of the OCT beam at consecutive surfaces. The principal direction of the tilt of the IOL mid-plane was then calculated with respect to the irido-corneal angle plane. The position of the IOL was also calculated as the post-operation measurement of the anterior chamber depth.

Results : The central 4 mm zone of the IOL could be imaged in all subjects. The tilt of the IOL in the four subjects are 4.1°, 6.3°, 6.7° and 10.7°. The cylinder component of refraction of the four subjects are -1.5D x 124°, -0.25D x 129°, -1D x 130°, -4.25D x 132° and the IOL position (post-op anterior chamber depth) are 4.3 mm, 4.8 mm, 4.6 mm, 4.3 mm in that order.

Conclusions : The study demonstrates the feasibility of quantifying sutureless scleral fixation IOL tilt using extended-depth OCT.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

 

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