June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Ultrasound Characteristics of Choroidal Metastases by Primary Tumor Site.
Author Affiliations & Notes
  • Octavio Turcio Aceves
    Retina y Vítreo, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Julian Garcia-Sanchez
    Retina y Vítreo, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Luis Antonio Antonio Rhoads Avila
    Retina y Vítreo, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Flor Angélica Jacome
    Retina y Vítreo, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Catalina Becerra Revollo
    Ultrasonography, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Ingrid Pita Ortiz
    Hospital Nuestra Señora de la Luz, Mexico
  • Daniel Moreno Páramo
    Retina y Vítreo, Hospital General de Mexico Dr Eduardo Liceaga, Ciudad de Mexico, Ciudad de Mexico, Mexico
  • Raquel Sánchez Santiago
    Ocular oncology, UMAE Hospital de Oncologia Centro Medico Nacional Siglo XXI, Ciudad de Mexico, Ciudad de México, Mexico
  • Guillermo Salcedo-Villanueva
    Retina y Vítreo, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Footnotes
    Commercial Relationships   Octavio Turcio Aceves None; Julian Garcia-Sanchez None; Luis Antonio Rhoads Avila None; Flor Jacome None; Catalina Becerra Revollo None; Ingrid Pita Ortiz None; Daniel Moreno Páramo None; Raquel Sánchez Santiago None; Guillermo Salcedo-Villanueva None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 302. doi:
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      Octavio Turcio Aceves, Julian Garcia-Sanchez, Luis Antonio Antonio Rhoads Avila, Flor Angélica Jacome, Catalina Becerra Revollo, Ingrid Pita Ortiz, Daniel Moreno Páramo, Raquel Sánchez Santiago, Guillermo Salcedo-Villanueva; Ultrasound Characteristics of Choroidal Metastases by Primary Tumor Site.. Invest. Ophthalmol. Vis. Sci. 2023;64(8):302.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Currently, there are few studies that compare ultrasonographic differences of choroidal metastases (CM) according to primary tumor site. The purpose was to determine the ultrasonographic features of CM according to primary tumor site.

Methods : This is a multi-center, retrospective, cross-sectional, observational, and comparative study. Data was obtained from 4 ophthalmological hospitals in Mexico: 1) Asociación Para Evitar la Ceguera en México (APEC); 2) Hospital General de México; 3) Fundación Hospital Nuestra Señora de la Luz; 4) Centro Médico Nacional Siglo XXI. The project had prior Institutional Review Board (IRB) approval and was adherent to the tenants of the Declaration of Helsinki.
The medical records of adult patients with CM diagnosed from 2000 to 2022 were retrospectively reviewed, recruiting patients diagnosed with CM who had a known primary cancer site and did not have treatment for choroidal metastases before ocular ultrasound.
Mann–Whitney U-test was used as a non-parametric test to compare groups of patients according to primary cancer site. Statistical analysis was performed with SPSS. Statistical significance was considered as P <0.05.

Results : Forty-seven patients were recruited, 59.57% (N=28) corresponding to females, 40.43% (N=19) to males. The age of presentation of the primary tumor had a mean of 56 years (25-81). The primary cancer site was breast in 23 patients (48.93%), lung in 9 (19.14%), gastrointestinal and kidney respectively in 4 (8.51%), prostate 2 (4.25%), testicle, thyroid, ovary, skin melanoma, and carcinoid respectively in 1 (2.12%).

CM reflectivity was statistically significant (p=0,05) when comparing breast (mean reflectivity of 80%; 95% confidence interval [CI] 58-92%) with lung (mean reflectivity of 67%; 95% CI 54-80). No statistically significant differences were found in terms of size.

Conclusions : CM from breast cancer have higher reflectivity by ultrasound compared to lung cancer. Our results could prove useful in the absence of any detectable primary cancer site.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

 

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