Abstract
Purpose :
Several evidence-based interventions are available for optometrists to slow childhood myopia. Measurement of axial length (AL) is important to monitor the success of these interventions, but traditional biometers are expensive and require significant space within optometric practice. The Myopia Master (MM), developed by Oculus, is an all-in-one instrument developed with clinical practice in mind which allows measurement and monitoring of refractive error and AL, however it is not yet known how measures obtained on this new device compare with traditional gold-standard instrumentation. This cross-sectional validation study compared measures from the Shin-Nippon NVisionK 5001 auto-refractor (NVK) and IOL Master 700 (IOL700) with measures from the MM in a predominantly Caucasian myopic population living in the UK.
Methods :
Fifty-six myopic children (mean age 11.93±1.95years; 50% female; 93% Caucasian) participated. Under full cycloplegia, the following measures were obtained by a First Examiner i) autorefraction (AR) using the NVK, ii) AL and corneal curvature (CC) using the IOL700, iii) AR, AL and CC using the MM. The latter measures were repeated by a Second Examiner to assess reproducibility of the MM. Bland-Altman analysis was used to determine agreement and reproducibility between measures.
Results :
AL measures exhibited excellent agreement between the IOL700 and MM with small mean differences (MD) and narrow Limits of Agreement (LOA) (MD 0.02mm, LOA -0.02 to 0.06mm). There was excellent reproducibility between Examiners (MD 0.00mm, LOA -0.04 to 0.04mm). AR measures demonstrated a moderate level of agreement between instruments (MD -0.44D, LOA -0.94 to 0.05D) and between Examiners (MD -0.03D, LOA -0.39 to 0.34D). Measurements obtained from the MM were on average more myopic than NVK. CC measurements demonstrated good agreement between instruments (MD 0.02mm, LOA -0.06 to 0.1mm) and excellent reproducibility (MD 0.01mm, LOA -0.04 to 0.05mm).
Conclusions :
The Myopia Master generates reliable measurements for AL and CC compared to the IOL700 in predominantly Caucasian myopic UK children. Moderate agreement for AR between MM and NVK was evident. Reproducibility of the MM between examiners was excellent across all measures. The Myopia Master is a good alternative, all-in-one instrument for use in myopia clinical trials and clinical practice to monitor myopia progression.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.