June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Cross-sectional study to evaluate the Notal Vision Home OCT (NVHO) for self-imaging and fluid quantification in eyes with Diabetic Macular Edema (DME)
Author Affiliations & Notes
  • Shelley Joy Levy
    Notal Vision Ltd, Tel Aviv, Tel Aviv, Israel
  • Jordana Goren Fein
    Retina Group of Washington, Greenbelt, Maryland, United States
  • Richard Garfinkel
    Retina Group of Washington, Greenbelt, Maryland, United States
  • Michael J Elman
    Elman Retina Group, Glen Burnie, Maryland, United States
  • Sidney A Schechet
    Elman Retina Group, Glen Burnie, Maryland, United States
  • Kapil G Kapoor
    Wagner Kapoor Institute, Virginia Beach, Virginia, United States
  • Alan L. Wagner
    Wagner Macula & Retina Center, Virginia Beach, Virginia, United States
  • Shiri Shulman
    Assuta Medical Center, Tel Aviv, Tel Aviv, Israel
  • Footnotes
    Commercial Relationships   Shelley Levy Notal Vision , Code E (Employment); Jordana Fein None; Richard Garfinkel None; Michael Elman Notal Vision , Code C (Consultant/Contractor), Notal Vision , Code I (Personal Financial Interest); Sidney Schechet Notal Vision , Code C (Consultant/Contractor); Kapil Kapoor None; Alan Wagner None; Shiri Shulman None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 1126. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Shelley Joy Levy, Jordana Goren Fein, Richard Garfinkel, Michael J Elman, Sidney A Schechet, Kapil G Kapoor, Alan L. Wagner, Shiri Shulman; Cross-sectional study to evaluate the Notal Vision Home OCT (NVHO) for self-imaging and fluid quantification in eyes with Diabetic Macular Edema (DME). Invest. Ophthalmol. Vis. Sci. 2023;64(8):1126.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To evaluate the usability of the NVHO in a cross-sectional study and quantify retinal fluid with an AI-based algorithm in eyes with DME

Methods : 93 eyes of 56 patients performed 2 to 5 (mean of 3.7) consecutive NVHO self-imaging sessions in a clinic setting resulting in a total of 288 volume scans. Retinal fluid was quantified using the Notal OCT Analyzer (NOA). Usability of the NVHO was assessed with median (IQR) of self-imaging duration and precent of successful attempts. Image quality was evaluated by the mean (SD) of manufacturer signal quality index (MSI – scale 1-7) as well as eligibility rate for retinal fluid volume quantification. Mean (SD) retinal fluid volume quantified by NOA as well as the fluid type, subretinal (SRF) or intraretinal (IRF) fluid (figure 1). In addition, the analysis included findings of hyperreflective foci (HF), diffuse retinal thickening (DRT) and hard exudates (HE). Automatic segmentation of these findings is being developed, and results will be shared by the authors during ARVO.

Results : The median (IQR) of self-imaging duration was 42 (36-60) seconds, the percent of successful attempts was 94% and the mean (SD) MSI was 4.1 (1.4), 85% of the volume-scans were eligible for retinal fluid quantification. Of the 74% eyes with fluid, 65% had a clinically meaningful amounts of fluid (>3 nL) with a mean (SD) of 95 (155) nanoliters. 4% of eyes had SRF, 33% had IRF and 63% had both SRF and IRF. HF, DRT and HE were identified on 63%, 9% and 42% of the eyes respectively.

Conclusions : The satisfactory self-imaging performance of patients with nv-AMD on the NVHO was previously reported. The current study reports similar results for DME patients. The range of fluid volume found is significantly larger than the volumes reported for nv-AMD eyes during the maintenance phase in the HARBOR study with mean SRF and IRF volumes of 39 and 24 nanoliters respectively. The frequency of clinic visits is expected to be reduced with the development of slow release and higher dosage drugs. However, to ensure improved clinical outcomes and protection of the fellow eye, a clear need for remote patient monitoring emerges. Self-imaging on the NVHO is speedy and together with automatic analysis NOA, may allow remote care with minimal burden on both the patient and the retina specialist.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

 

Automatic Retinal Fluid Segmentation

Automatic Retinal Fluid Segmentation

 

Rpeated Self-Imaging

Rpeated Self-Imaging

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×