Abstract
Purpose :
Objectively assess the status of posterior vitreous detachment (PVD) and occurrence of Vitreous Floaters and Opacities (VFO) in consecutive patients.
Methods :
Retrospective study of 453 consecutive patients (906 eyes) who underwent complete ophthalmological examination between February 2020 and January 2022. All patients underwent best-corrected visual acuity (BCVA), slit-lamp biomicroscopy (Slit lamp, Topcon SL-D701), indirect ophthalmoscopy (Slimline Lithium-Ion Vantage Plus, Keeler) with scleral indentation, multi-wavelength ultra-widefield imaging (MW UWF) (Optos California, Optos Inc, Marlborough, MA, USA) and 23 mm single-capture 3D and cross-sectional widefield (WF) swept-source optical coherence tomography (SS-OCT) (Xephilio OCT Canon S1, Canon Medical Systems Europe, Zoetermeer, The Netherlands).
All analyses were performed using the SPSS version 22.0 statistical package (SPSS, Chicago, IL, USA).
Results :
The mean age was 51.32±0.59 years. 229 subjects were male (50.55%).
The most common refractive error was high myopia (n=208, 23%), followed by simple myopia (n=195,21.5%) and hyperopia (n=146,16.1%).
A complete PVD was observed in 202 out of 906 eyes (22.30%) and its prevalence was higher in the age group 50-89 (n=182) compared to younger patients in age groups 18-49 (n=20). Partial PVD was present in 45 eyes (5%) and similarly observed throughout all patient age groups from 24 to 69 years of age. Mean axial length and refractive error in eyes with complete PVD were 28.21±3.00 mm and -3.00±5.12 D, respectively. PVD presented a higher prevalence in simple myopic (n=47) (p=0.37) and high myopic eyes (n=53) (p=0.05). No refractive differences were correlated with partial PVD. The occurrence of PVD was linked to the presence of a Weiss Ring (43.13%), as well as the presence of VFO (91.89%). VFO were found in 181 subjects (20.07%) and imaged as hyperreflective dots in the vitreous casting a shadow onto the retina using the WF SS-OCT. Vitreous synchysis was presented in 138 eyes (15.2%), 39 with simple myopia (p=0.036) and 21 with high myopia (p=0.019).
Conclusions :
We here present a new powerful diagnostic imaging device that provides high-resolution images of the vitreous, the vitreoretinal interface and VFO and that can help to objectively assess the status of PVD and the characteristics of VFO.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.