Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Lateral eye movements reveal dynamics of the tear film margins
Author Affiliations & Notes
  • Timon Ax
    Western Sydney University School of Medicine, Penrith South DC, New South Wales, Australia
    Ophthalmology, Universitatsklinikum des Saarlandes und Medizinische Fakultat der Universitat des Saarlandes, Homburg, Saarland, Germany
  • Francesc March de Ribot
    Ophthalmology, Otago Medical School, Dunedin, New Zealand
  • Slade Owen Jensen
    Western Sydney University School of Medicine, Penrith South DC, New South Wales, Australia
    Antimicrobial Resistance and Mobile Elements Group, Ingham Institute, Liverpool, New South Wales, Australia
  • Berthold Seitz
    Ophthalmology, Universitatsklinikum des Saarlandes und Medizinische Fakultat der Universitat des Saarlandes, Homburg, Saarland, Germany
  • Thomas James Millar
    School of Biology, Western Sydney University, Penrith South, New South Wales, Australia
  • Footnotes
    Commercial Relationships   Timon Ax Beyond 700 Pty Ltd, Code F (Financial Support); Francesc March de Ribot None; Slade Jensen None; Berthold Seitz None; Thomas Millar Beyond 700 Pty Ltd, Code E (Employment)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 6549. doi:
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    • Get Citation

      Timon Ax, Francesc March de Ribot, Slade Owen Jensen, Berthold Seitz, Thomas James Millar; Lateral eye movements reveal dynamics of the tear film margins. Invest. Ophthalmol. Vis. Sci. 2024;65(7):6549.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Lateral eye movements are natural and common but the effects of the eye moving on tear film behavior are largely unknown. These lateral eye movements are not considered during eye examinations because subjects are required to look straight ahead. This study is to determine what happens to the tear film during lateral eye movements.

Methods : 15 participants (10 male, 5 female; mean age 26 with two male outliers age 70) had no ocular surface related complaints (OSDI <13) and no fluorescein staining. Tear film dynamics of a sequence of open-eye gaze maneuvers (saccadic abduction-adduction, finger following) were recorded in real time using a TearView camera system. This detects the tear film based on natural infrared emission from the ocular surface. The study was non-interventional, observational and did not involve a control group.

Results : Lateral eye movements expose new ocular surface not previously covered by the tear film.
The tear film margins react to eye movements by spreading towards the newly uncovered ocular surface areas, thereby recoating them. Additional flow comes from a tear reservoir around the caruncle. No flow occurs from the menisci onto the ocular surface.

Conclusions : Lateral eye movements rip the tear film away from the lid margins. The sheer forces fluidize the existing tear film allowing it to flow towards the newly exposed ocular surface. In addition, a reserve of tears around the caruncle provides an immediate buffer for filling in this gap in the tear film. It is speculated that this tear reservoir would be diminished in patients with dry eye and so the ocular surface would remain exposed. This complex behavior of the tear film during lateral gaze also needs to be considered in oculoplastic surgery of the canthal regions.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

New tear film (pale area bordered by arrows) being "drawn” out of the lacrimal triangle during an abduction maneuver in a right eye.

New tear film (pale area bordered by arrows) being "drawn” out of the lacrimal triangle during an abduction maneuver in a right eye.

 

No tear film being drawn out of the lateral canthus during an adduction maneuver in the same right eye. Tear film retains canthal shape initially (dark arcuate line to the left).

No tear film being drawn out of the lateral canthus during an adduction maneuver in the same right eye. Tear film retains canthal shape initially (dark arcuate line to the left).

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