Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Geographic Disparities in Glaucoma Surgical Care: An Intelligent Research in Sight (IRIS) Registry Analysis
Author Affiliations & Notes
  • Anagha Lokhande
    Harvard Ophthalmology AI Lab, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
    Brown University Warren Alpert Medical School, Providence, Rhode Island, United States
  • Kanza Aziz
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Louis R. Pasquale
    Eye and Vision Research Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States
  • Lucy Q Shen
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • David S Friedman
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Michael V Boland
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Alice Carlyle Lorch
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Joan W Miller
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Mengyu Wang
    Harvard Ophthalmology AI Lab, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Nazlee Zebardast
    Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Tobias Elze
    Harvard Ophthalmology AI Lab, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Footnotes
    Commercial Relationships   Anagha Lokhande None; Kanza Aziz None; Louis Pasquale Twenty-Twenty, Character Bio, Code C (Consultant/Contractor); Lucy Shen FireCyte Therapeutics, Code C (Consultant/Contractor); David Friedman Thea Pharmaceuticals, AbbVie, Life Biosciences, Code C (Consultant/Contractor), Genentech, Code F (Financial Support); Michael Boland Carl Zeiss Meditec, Topcon, Allergan, Janssen, Code C (Consultant/Contractor); Alice Lorch Regeneron, Code C (Consultant/Contractor); Joan Miller None; Mengyu Wang Genentech, Code F (Financial Support); Nazlee Zebardast None; Tobias Elze Genentech, Code F (Financial Support)
  • Footnotes
    Support  NIH K23 5K23EY032634, NIH R21 5R21EY032953, Research to Prevent Blindness Career Development Award, NIH P30 EY003790, NIH R00 EY028631, NIH R21 EY035298, Research to Prevent Blindness International Research Collaborators Award, Alcon Young Investigator Grant, Grimshaw-Gudewicz Grant
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4638. doi:
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      Anagha Lokhande, Kanza Aziz, Louis R. Pasquale, Lucy Q Shen, David S Friedman, Michael V Boland, Alice Carlyle Lorch, Joan W Miller, Mengyu Wang, Nazlee Zebardast, Tobias Elze; Geographic Disparities in Glaucoma Surgical Care: An Intelligent Research in Sight (IRIS) Registry Analysis. Invest. Ophthalmol. Vis. Sci. 2024;65(7):4638.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To quantify differences in glaucoma surgeries based on geography and practice/provider characteristics.

Methods : IRIS Registry data from 2013 – 2020 were included. Cases of micro-invasive glaucoma surgery (MIGS, i.e., iStent microstent, endocyclophotocoagulation, XEN Gel Stent, goniotomy or ab interno trabeculotomy or Trabectome, and canaloplasty) and filtering glaucoma surgery (glaucoma drainage device [GDD] and trabeculectomy) associated with glaucoma diagnosis (with severity stratified by the International Classification of Diseases, Ninth and Tenth Revisions) were selected based on Current Procedure Terminology codes. Urbanization of practice zip codes was classified using Rural-Urban Commuting Area Codes from the United States (US) Department of Agriculture. Associations between procedure counts and practice, provider, and geographic characteristics were assessed using chi-square tests and multivariate logistic regression adjusted for patient demographics (age, gender, and race), glaucoma severity, the interaction between glaucoma severity and urban location, and, as provided by the US Census, zip code population density. Statistical significance was set at p < 0.05.

Results : Most glaucoma surgeries were performed in ophthalmology group practices (55.2%) and urban locations (90.8%). Glaucoma subspecialists performed 72.9% of GDD surgeries, 63.4% of XEN Gel stent surgeries, and 69.0% of trabeculectomies (Table 1). Figure 1 shows the geographic distribution of glaucoma procedures in the mainland US. Urban practice location was associated with a lower likelihood of receiving an iStent (odds ratio [OR] = 0.43, p < 0.0001) and higher odds of receiving endocyclophotocoagulation (OR = 2.23), goniotomy or canaloplasty (OR = 1.57), GDD (OR = 1.85), and trabeculectomy (OR = 1.59) (p < 0.0001). No significant association was found between urban practice location and the likelihood of XEN Gel stent.

Conclusions : Ophthalmology group practices and practices in urban areas account for most glaucoma surgeries. Glaucoma subspecialists performed most filtering glaucoma surgeries. Urban practice location is a significant predictor of receiving most types of MIGS and filtering glaucoma surgery, which may represent barriers to accessing complex surgical glaucoma care for patients outside urban areas.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

 

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