Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
The Impact of Pupil Size on Myopia Control with Multifocal Contact Lenses: A Comparative Study of MYLO and MiSight
Author Affiliations & Notes
  • Pablo De Gracia
    School of Optometry, University of Detroit Mercy, Detroit, Michigan, United States
  • Keyur Savla
    School of Optometry, University of Alabama at Birmingham, Birmingham, Alabama, United States
  • Andrew David Pucker
    Lexitas Pharma Services, North Carolina, United States
  • Footnotes
    Commercial Relationships   Pablo De Gracia Mark'ennovy, Code C (Consultant/Contractor); Keyur Savla None; Andrew Pucker Lexitas Pharma Services, Code E (Employment)
  • Footnotes
    Support  Free Contact Lenses from Mark'ennovy
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 2744. doi:
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      Pablo De Gracia, Keyur Savla, Andrew David Pucker; The Impact of Pupil Size on Myopia Control with Multifocal Contact Lenses: A Comparative Study of MYLO and MiSight. Invest. Ophthalmol. Vis. Sci. 2024;65(7):2744.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Multifocal contact lenses (MCLs) hinder myopia progression. MCL power changes as a function of the radius. In this study, we explore how pupil size affects the through-focus optical properties of two lenses commonly used for myopia control: MYLO and MiSight.

Methods : Sagittal power profiles for MYLO and MiSight lenses were measured using a NIMO instrument (Lambda-X). MYLO lenses covered prescription powers from 0.00 D to -6.00 D in -0.50 D steps, while MiSight lenses covered -0.50 D, -1.00 D, -2.00 D, -3.00 D, -4.00 D, -5.00 D, and -6.00 D. Visual Strehl on the Frequency Domain (VSOTF) for all lenses was calculated across focus (193 steps from -1.00 to 5.00 diopters) for pupil sizes ranging from 0.5 to 7 mm in 0.5 mm increments on a diffraction-limited eye and compared to the performance observed with a monofocal lens. Subsequently, the theoretical assessment of MiSight and MYLO lenses was integrated with low- and high-order aberrations from a database of 65 eyes with pupils ranging from 2.45 mm to 6.27 mm. In all cases, optical quality in front of the retina was compared to that behind the retina for one- and two-diopter intervals.

Results : In an ideal eye, MYLO and MiSight lenses demonstrate superior optical quality pre-retina compared to a monofocal lens. MYLO designs excel with smaller pupil sizes (<3.00 mm), while MiSight lenses show increased disparity between in front and behind the retinal plane for pupils around 5 mm. Results for two and one diopter intervals are highly similar, with the primary distinction being the smoother performance of the two-diopter interval. When aberrations of a database of 65 subjects are considered, MiSight lenses exhibit enhanced myopia control for larger pupil sizes, while MYLO lenses are more effective for smaller pupils.

Conclusions : Both MYLO and MiSight lenses outperform monofocal lenses in terms of optical quality in an ideal eye, exhibiting superior performance pre-retina. Notably, MYLO lenses demonstrate a proficiency for smaller pupil sizes (<3.00 mm), while MiSight lenses exhibit increased disparity between in front and behind the retinal plane, particularly for pupils around 5 mm. When considering low- and high-order aberrations from a database of 65 subjects, our results suggest that MiSight lenses offer superior myopia control for larger pupil sizes, whereas MYLO lenses prove more effective for subjects with smaller pupils.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

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