In-Home Use Test of a Novel Contact Lens Solution in Contact Lens Wearers on the Verge of Dropout

Abstract

Purpose : Contact lens (CL) dropout rates have been estimated to be 12%–27%, with discomfort as the main reason.¹ CL dropout can be reduced by early detection, patient education, and providing alternate options for CL wear/care.¹ A new multi-purpose solution (MPS) including moisturizers hyaluronan, poloxamine 1107, poloxamer 181, an electrolyte (potassium), and an osmoprotectant/antioxidant (erythritol) was developed to improve comfort. This real-world in-home use test assessed the performance of the Biotrue Hydration Plus MPS among users who planned to stop wearing CLs in the next 6 months due to discomfort.

Methods : Soft CL users were recruited online via consumer panel providers. Eligible participants had to be aged ≥18 years, a habitual user of soft CLs (min 3 hours/day and 4 days/week), to have had an eye exam within the last 2 years, to have knowledge of disinfectant solution brand used, and to have never had an allergic reaction to MPS.

Participants who planned to stop wearing CLs in the next 6 months due to discomfort or eye dryness were asked to use the MPS for 7 days, with a new pair of CLs, before completing an online survey (7-pt Likert scale). At least 60% of interviews were validated via follow-up phone calls.

A two-sided exact binomial test was performed to test whether agreement was indicated for more than 50% of responses for the performance attributes.

Results : 202 participants (mean age 40.6, 64.9% male) used the MPS for at least 5 days. After use, 88.6% agreed they would be more likely to keep wearing CLs, and 90% agreed that using the new MPS had positively impacted the comfort of their CLs. Perceptions of other performance attributes are summarized in Table 1. In terms of overall satisfaction, 97.5% said they were satisfied. Agreement responses were significantly greater than 50% for all performance attributes.

Conclusions : Biotrue Hydration Plus MPS provided positive performance results in participants who were on the verge of giving up on CL wear, demonstrating the positive and important impact a MPS can have on helping to prevent CL dropout.

1. Pucker AD, Tichenor AA. A Review of Contact Lens Dropout. Clin Optom (Auckl) 2020; doi: 10.2147/OPTO.S198637.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

Table 1. Percent agreement includes participants who answered strongly agree, agree or slightly agree.