Myopia control efficacy of Spectacle Lenses with Highly Aspherical Lenslets: results of a 5-year follow-up study

Abstract

Purpose : To investigate the myopia control efficacy of wearing spectacle lenses with highly aspherical lenslets (HAL) continuously for 5 years in Chinese children.

Methods : Fifty-one children who had been wearing HAL for three years were invited to continue wearing them for two additional years. The change in spherical equivalent of cycloplegic autorefraction (SER) and axial length (AL) with HAL was compared to a single vision lens (SVL) control group model. This model was based on SVL data from the first two years of the same clinical trial (Bao, et al. JAMA Ophthalmology 2022; May 1;140(5):472-478), with a predicted average annual decrease in SER by 9.7% (Smotherman C, et al. IOVS 2023;64:ARVO E-Abstract 811) and in AL by 15% (Shamp W, et al. IOVS 2022;63:ARVO E-Abstract A0111).

Results : The control group model predicted a 5-year increase in SER (±SE) and AL (±SE) of -3.03±0.18 D and 1.40±0.07 mm in children wearing SVLs, respectively. The 43 participants from the HAL group who completed the five-year visit were aged (±SD) 14.7±1.1 years (13 to 18). Their mean (±SE) change in SER and AL over 5 years was -1.27±0.14 D and 0.67±0.06 mm, respectively. The 5-year estimated myopia control efficacy of HAL lenses compared to the modeled control group was 1.76 D (58%) and 0.73 mm (52%).

Conclusions : Spectacle lenses with highly aspherical lenslets (HAL) were effective in slowing down myopia progression and axial elongation over five years.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.