Abstract
Purpose :
To describe a case of bilateral stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) which resolved completely and spontaneously without a change in the vitreoretinal interface.
Methods :
Observational case report
Results :
A 38-year-old woman presented to clinic for a second opinion regarding macular schisis in the left eye that was first noted one year prior. The patient had previously been trialed on topical prednisolone and subtenon triamcinolone without resolution of schisis. On examination, the patient was found to have schisis-like foveal thickening with no lipid, pigment changes, or microvascular abnormalities in the left eye. Additionally, shallow peripheral retinoschisis was observed in both eyes. OCT showed foveal schisis in the outer plexiform layer with wider splitting in the inner nuclear layer. There was no evidence of epiretinal membrane or vitreomacular traction. Further testing revealed no leakage on fluorescein angiography, normal ERG, and normal Goldmann visual field. The patient was trialed on oral acetazolamide as well as topical ketorolac and brinzolamide without response. One year after initial presentation, a similar macular schisis had developed in the fellow eye. The patient was monitored without further intervention. Four years after initial presentation, the macular schisis had completely resolved bilaterally. The patient reported no changes in medication, no new medical conditions, and no changes in diet or physical activity. There was no change in the vitreoretinal interface in either eye.
Conclusions :
Although spontaneous resolution of presumed SNIFR following OCT-documented vitreomacular adhesion release has been previously reported, to our knowledge this is the first reported case of complete bilateral resolution of SNIFR without a change in the vitreoretinal interface.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.