Abstract
Purpose :
To assess the outcomes of Selective Laser Trabeculoplasty (SLT) in patients with severe open-angle glaucoma (OAG) and closed-angle glaucoma (CAG).
Methods :
This is a retrospective study which includes 71 eyes with severe OAG and CAG who received SLT during March-August 2023, at Instituto de Oftalmologia Conde de Valenciana, Mexico City. In order to evaluate the outcomes of SLT, IOP was compared before SLT and at 6 weeks and 3 months after this therapy; number of hypotensive ocular drugs before and after SLT, as well as the realization of a glaucoma surgery after SLT. For statistical analysis, Friedman and Wilcoxon tests were used. The level of significance was set as p= <0.05 for all tests. Results are expressed in mean +/- standard deviation (SD).
Results :
After SLT, the number of hypotensive ocular drugs reduced from 2.94 +/-1.1 to 2.2 +/-1.4 (p=<0.0001). IOP reduced from 14.37 +/- 5.03 to 13.37 +/-3.68 at 6 weeks and 13.65 +/-4.20 at 3 months (p=<0.33). Mean deviation from visual fields was -16.34 +/-7.15. In 9 cases, glaucoma progression continued and either trabeculectomy or Ahmed Valve were performed.
Conclusions :
SLT in cases of severe OAG and CAG is effective in reducing the number of hypotensive ocular drugs. For 3 months, SLT avoids the need of a glaucoma surgery in severe cases. IOP was not statistically reduced after SLT, therefore we need more data and follow-up to know the effect of this therapy on reducing IOP.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.