Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Effects of capsulorhexis size and position on post-surgical IOL alignment.
Author Affiliations & Notes
  • Liying Feng
    Universiteit Antwerpen, Antwerpen, Belgium
    R&D, Johnson and Johnson Vision, Groningen, Netherlands
  • Carmen Canovas
    R&D, Johnson and Johnson Vision, Groningen, Netherlands
  • Henk A Weeber
    R&D, Johnson and Johnson Vision, Groningen, Netherlands
  • Bram Koopman
    R&D, Johnson and Johnson Vision, Groningen, Netherlands
  • Shima Bahramizadeh Sajadi
    R&D, Johnson and Johnson Vision, Groningen, Netherlands
  • Jos J Rozema
    Universiteit Antwerpen, Antwerpen, Belgium
  • Footnotes
    Commercial Relationships   Liying Feng Johnson & Johnson Vision, Code E (Employment); Carmen Canovas Johnson & Johnson Vision, Code E (Employment); Henk Weeber Johnson & Johnson Vision, Code E (Employment); Bram Koopman Johnson & Johnson Vision, Code E (Employment); Shima Bahramizadeh Sajadi Johnson & Johnson Vision, Code E (Employment); Jos Rozema University of Antwerp, Code E (Employment)
  • Footnotes
    Support  Marie Skłodowska-Curie grant agreement No 956720
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 2073. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Liying Feng, Carmen Canovas, Henk A Weeber, Bram Koopman, Shima Bahramizadeh Sajadi, Jos J Rozema; Effects of capsulorhexis size and position on post-surgical IOL alignment.. Invest. Ophthalmol. Vis. Sci. 2024;65(7):2073.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : The IOL stability in the capsular bag after the surgery largely affects the visual quality for the patients. This work explores how the size and decentration of capsulorhexis affect intraocular lens decentration and tilt by finite element modeling.

Methods : To assess the biomechanical stability of the intraocular lens in the capsular bag, a finite element model was built of a capsular bag with capsulorhexis of different sizes and centration based on literature data (Burd 2002). The effect of capsulorhexes on IOLs with different powers was compared.
Decentration and tilt were calculated to assess the IOL mechanical stability. The long axis and short axis of the capsular bag were measured to asses its deformation. The finite element models in the study included capsular bag with capsulorhexis, IOL, zonular fibers and ciliary body. Axial movement of IOL was recorded. 4.5 mm and 5.5 mm diameter capsulorhexis were applied in the simulation, and the capsulorhexis was moved 0.5 mm or 1 mm in two perpendicular directions normal to the optical axis. The results were compared with currently published numerical and clinical studies.

Results : Models featuring a centered 4.5 mm capsulorhexis demonstrated minimal intraocular lens (IOL) decentration (0.55 µm) and tilt (0.082°). Depending on capsulorhexis centration, IOL centration ranged from 0.51 to 2.45 µm, while tilt varied between 0.064° and 0.90°. In cases where a 5.5 mm capsulorhexis was centered, the IOL exhibited decentration of 0.43 µm and tilt of 0.084°. Conversely, a decentered capsulorhexis led to IOL decentration ranging from 1.28 to 8.30 µm, and tilt from 0.021° to 0.65°. These findings, notably smaller than clinically reported values (0.1 - 0.5 mm for IOL decentration and 0.1 - 2° for tilt), suggest a relatively stable IOL position.
Furthermore, IOLs with powers of 5 D, 20 D, and 34 D displayed limited magnitude difference on decentration, tilt, and axial movement, indicating that these differences are unlikely to result in discernible clinical consequences.

Conclusions : The model suggests that capsulorhexis size and decentration have only a minor effect on IOL decentration or tilt that will in most cases not be noticeable to the patient. The differences caused by IOL powers are not noticeable according to the simulation.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

 

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×