Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Inspiring interest in eye research by bridging engineering and ophthalmology in high school
Author Affiliations & Notes
  • Michael Murphy
    John Bapst Memorial High School, Bangor, Maine, United States
  • Giovanna Guidoboni
    University of Maine, Orono, Maine, United States
  • Giuseppe Aulisa
    John Bapst Memorial High School, Bangor, Maine, United States
  • Logan Hart
    John Bapst Memorial High School, Bangor, Maine, United States
  • Ethan Marquis
    John Bapst Memorial High School, Bangor, Maine, United States
  • Lorena Bociu
    Mathematics, NC State University, Raleigh, North Carolina, United States
  • Alon Harris
    Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York, United States
  • Footnotes
    Commercial Relationships   Michael Murphy None; Giovanna Guidoboni Qlaris, Foresite Healthcare LLC, Code C (Consultant/Contractor), Gspace LLC, Code O (Owner); Giuseppe Aulisa None; Logan Hart None; Ethan Marquis None; Lorena Bociu None; Alon Harris AdOM, Qlaris, Cipla, Code C (Consultant/Contractor), AdOM, Qlaris, Oxymap, SlitLED, Code I (Personal Financial Interest), AdOM, Qlaris, Code S (non-remunerative)
  • Footnotes
    Support  This work has been partially supported by NIH R01EY030851, NIH R01EY034718, NSF-DMS 2108711/2327640, NYEE Foundation grants, and in part by a Departmental Challenge Grant award from Research to Prevent Blindness, NY.
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4217. doi:
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      Michael Murphy, Giovanna Guidoboni, Giuseppe Aulisa, Logan Hart, Ethan Marquis, Lorena Bociu, Alon Harris; Inspiring interest in eye research by bridging engineering and ophthalmology in high school. Invest. Ophthalmol. Vis. Sci. 2024;65(7):4217.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To bridge engineering and ophthalmology research in a high school course that inspires discovery-driven learning and critical thinking via cutting-edge research applications.

Methods : The content of Engineering I (John Bapst Memorial High School, ME, USA) was redesigned to learn engineering design process, documentation, modeling, research techniques, and iteration by addressing cutting-edge research questions in ophthalmology. The course learning objectives are summarized in Fig. 1. Starting from common reading and discussion of published research articles, students are prompted to identify interesting engineering questions within the field, formulate the problem statement, design experiments and protocols to investigate the problem, iterate to fine-tune the strategy, and present the process and the results in a professional manner.

Results : Offered in Fall 2023, the course enrolled 21 students in grades 9-12 (Fig.1), who were divided into 6 groups with 3-5 students per group. Each group self-selected eye-related engineering questions, including building a physical model to simulate how the ocular vasculature may respond to changes in pressure inside or outside the vessels (Fig. 2). Much effort was put into finding appropriate materials to use to mimic human tissues. The utility of liquid latex, which can be applied in layers over a dissolvable 3D printed mold was a favored approach. Another group looked at an electric circuit design that is used as an analog for the blood flow in the intraocular region, and built and tested the electrical circuit in its physical form.

Conclusions : Through study of the eye and design of models consistent with its properties, students developed significant appreciation for and knowledge of ocular anatomy and physiology. Student learning was driven by real problems, yielding a higher level of engagement and ownership than previous years. Students have been exposed to peer reviewed research, learning how to read and decipher work that is years ahead of their educational level. Intentionally integrating engineering and ophthalmology may help excite the next generations of scientists and clinicians who will work effectively and collaboratively to advance disease understanding, cure, and care.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

Learning objectives and course enrollment

Learning objectives and course enrollment

 

Students' design to study the ocular vascular response to changes in internal and external pressure (a). CAD design of 3D printed vessels (b,c) and of the overall system (d).

Students' design to study the ocular vascular response to changes in internal and external pressure (a). CAD design of 3D printed vessels (b,c) and of the overall system (d).

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