Abstract
Purpose :
To investigate the vision rehabilitation effect of rigid gas permeable contact lenses (RGPCLs) in children with primary congenital glaucoma (PCG).
Methods :
This is a cross-sectional analysis of the baseline data of a randomized controlled trial investigating impact of RGPCL on visual rehabilitation of PCG children with controlled intraocular pressure. Refractive errors were corrected by spectacles at first, then RGPCLs. Best spectacle corrected and RGPCL corrected visual acuities, as well as contrast sensitivity functions (CSF), were compared.
Results :
A total of 51 PCG eyes (from 29 children) were analyzed in this study. Better best corrected visual acuity (BCVA) and CSF were observed with RGPCLs correction than with spectacles [0.30 (0.15, 0.52) vs. 0.40 (0.30, 0.70) logMAR for BCVA, 0.68±0.38 vs. 0.51±0.33 for area under log CSF (AULCSF), and 0.94±0.29 vs. 0.83±0.29 for CSF Acuity, all P＜0.001]. In multivariate linear regressions, greater myopic spherical equivalent (SER) showed significant associations with improvement in BCVA (β= -0.07, [95% CI] [-0.11, -0.02]; P＜0.001) and CSF Acuity (β= -0.01, [95% CI] [-0.01, -0.00]; P=0.03).
Conclusions :
RGPCLs can immediately improve the visual function of PCG children. The study results indicate that RGPCLs are potentially useful for visual rehabilitation in such children.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.