Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Use of a Handheld Ultrasound Device for Detecting Orbital Inflammation
Author Affiliations & Notes
  • Aashka Damani
    University of Washington School of Medicine, Seattle, Washington, United States
  • Connor Nathe
    University of Washington, Seattle, Washington, United States
  • Preston Thomas
    University of Washington School of Medicine, Seattle, Washington, United States
  • Alexandra Van Brummen
    University of Washington, Seattle, Washington, United States
  • Kasra Rezaei
    University of Washington, Seattle, Washington, United States
  • Shu Feng
    University of Washington, Seattle, Washington, United States
  • Footnotes
    Commercial Relationships   Aashka Damani None; Connor Nathe None; Preston Thomas None; Alexandra Van Brummen None; Kasra Rezaei None; Shu Feng None
  • Footnotes
    Support  Latham Vision Research Innovation Award, Research to Prevent Blindness
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 5895. doi:
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      Aashka Damani, Connor Nathe, Preston Thomas, Alexandra Van Brummen, Kasra Rezaei, Shu Feng; Use of a Handheld Ultrasound Device for Detecting Orbital Inflammation. Invest. Ophthalmol. Vis. Sci. 2024;65(7):5895.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Orbital sonography is a safe, fast, non-invasive imaging modality for evaluation of orbital inflammatory diseases at bedside; there are newer smart-phone-based handheld ultrasound devices that have been used in emergency and hospital settings. This study aims to assess the performance of a handheld ultrasound device in detecting orbital inflammation.

Methods : This cross-sectional study of patients assessed the efficacy of the Butterfly IQ+ (Butterfly Network, Burlington, MA) portable ultrasound device for detecting orbital inflammation in patients presenting to Harborview Medical Center with concern for pre-septal or orbital cellulitis between April and June 2022. A trained examiner imaged bilateral orbits of participants in two planes at a fixed depth of 4 cm and recorded dynamic video of the exam. Each subject’s clinical ophthalmic diagnoses from same day exam and computed tomography (CT) scan were recorded, and a blinded reader assessed scans for presence or absence of orbital inflammation.

Results : Twelve total subjects were imaged, 6 with orbital inflammation, and 6 with pre-septal cellulitis. All 6 subjects with orbital inflammation were correctly identified, and all 6 subjects without orbital inflammation were correctly identified by the blinded reader. The handheld ultrasound probe was able to capture features consistent with concurrent CT scans, including the presence of orbital abscess in 4 subjects. Limitations of the device include a large probe that may not anatomically be feasible for patients with deep orbits.

Conclusions : The Butterfly IQ+ ultrasound device was highly effective in identifying orbital inflammation and orbital abscesses. The non-invasive nature of ultrasound makes it promising for serial scans to monitor patients’ response to treatment over time, especially in the pediatric population where radiation exposure from CT is a concern.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

Figure 1: Preseptal cellulitis demonstrated on the CT (top), and Butterfly IQ+ ultrasound image, with hyper-echoic area anteriorly.

Figure 1: Preseptal cellulitis demonstrated on the CT (top), and Butterfly IQ+ ultrasound image, with hyper-echoic area anteriorly.

 

Figure 2. The CT demonstrates an orbital abscess, seen as a peripherally enhancing fluid collection (red arrow) in the inferomedial extraconal left orbit, extending to the nasolacrimal duct. On handheld ultrasound scan, this manifests again as a hypo-echoic area (blue arrow) with scattered hyper-echoic contents.

Figure 2. The CT demonstrates an orbital abscess, seen as a peripherally enhancing fluid collection (red arrow) in the inferomedial extraconal left orbit, extending to the nasolacrimal duct. On handheld ultrasound scan, this manifests again as a hypo-echoic area (blue arrow) with scattered hyper-echoic contents.

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