Abstract
Purpose :
A preliminary study to assess the repeatability and reproducibility of Solix Corneal Topography measurements and compare them with Pentacam in normal eyes. Key parameters under investigation include steep keratometry (K1), flat keratometry (K2), maximum keratometry (Kmax), mean keratometry (Kmean) for both anterior and posterior surfaces, as well as Total Corneal Power of the central 3mm area (TCP_3mm) and central 6mm area (TCP_6mm). The evaluation utilizes the Corneal Topography feature in the Solix SD-OCT device (Visionix, San Jose, CA).
Methods :
Following Institutional Review Board (IRB) approval, a repeatability and reproducibility study was conducted using two Solix devices on 10 normal eyes. Three Corneal Map scans were obtained for each eye, and measurements of K1, K2, Kmax, and Kmean were computed for both anterior and posterior corneal surfaces. Total Corneal Power of the central 3mm area (TCP_3mm) and central 6mm area (TCP_6mm) was also calculated. Additionally, an agreement study was conducted on 15 normal eyes using one Solix device and one Pentacam device. Three scans were collected on both Solix and Pentacam. Limits of Agreement (LOA) and Deming regressions were employed to assess the agreement of K1 and K2 of the anterior surface.
Results :
Table 1 presents the mean, minimum, maximum values, repeatability standard deviations (std), reproducibility std, and intraclass correlation coefficient (ICC) for K1, K2, Kmax, Kmean of the anterior and posterior corneal surfaces, as well as TCP_3mm and TCP_6mm. Deming regression slopes range within 0.989-0.997 for K1 and 0.987-0.996 for K2.
Conclusions :
Solix Corneal Topography measurements demonstrate good repeatability and reproducibility with ICC values well exceeding 0.9. They exhibit reasonable agreement with measurements obtained from Pentacam. This study affirms that Solix is a reliable option for Corneal Topography, complementing its FDA-cleared Anterior & Posterior OCT/OCTA measurements.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.