Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Characteristics and visual predictors analysis for surgically treated laser-induced full-thickness macular holes
Author Affiliations & Notes
  • Ying Cui
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Tongren Eye Center, Beijing, China
  • Wu Liu
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Tongren Eye Center, Beijing, China
  • Ya Xing Wang
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Tongren Eye Center, Beijing, China
    Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing, China
  • Xiangyu Shi
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Tongren Eye Center, Beijing, China
  • Footnotes
    Commercial Relationships   Ying Cui None; Wu Liu None; Ya Xing Wang None; Xiangyu Shi None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4028. doi:
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    • Get Citation

      Ying Cui, Wu Liu, Ya Xing Wang, Xiangyu Shi; Characteristics and visual predictors analysis for surgically treated laser-induced full-thickness macular holes. Invest. Ophthalmol. Vis. Sci. 2024;65(7):4028.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To report the characteristics and the visual and anatomical outcomes of surgically treated full-thickness macular holes (MHs) accidentally caused by laser devices and analyse the visual predictors.

Methods : All 28 consecutive patients who underwent vitrectomy for laser-induced MHs at Beijing Tongren eye center from August 2013 to April 2023 were included. The minimum follow-up time after surgery was 6 months. A full ophthalmic examination and optical coherence tomography (OCT) were used for assessment at baseline and at follow-ups.

Results : 11 patients were accidentally injured by an yttrium aluminum garnet (YAG) laser and 17 by a handheld laser. The MH minimum diameters (MDs) ranged from 218 to 1152μm (mean, 525.0 ± 227.0μm). 5 patients had a focal subfoveal choroidal depression preoperatively. Preoperative bestcorrected visual acuity (BCVA) was associated with preoperative MD (P=0.021, B=0.040, 95%CI: 0.007~0.073). BCVA improved from 0.846 ± 0.370 logMAR preoperatively to 0.523 ± 0.443 logMAR postoperatively (P<0.001, t =4.192). MH closure was achieved in 89.3% eyes. Visual acuity (VA) improvement of at least 2 lines of Snellen’s visual acuity was observed in 65.2% eyes. VA improvement was associated with preoperative choroidal depression (P=0.035, OR=0.071, 95%CI: 0.006~0.834). Final VA (logMAR) was associated with preoperative choroidal depression (P=0.020, B=0.507, 95%CI: 0.090~0.924), preoperative BCVA (P=0.002, B=0.719, 95%CI: 0.284~1.153), final MH closure status (P=0.012, B=-0.664, 95%CI: -1.163~-0.164), postoperative ellipsoid zone (EZ) defect (P=0.017, B=0.054, 95%CI: 0.012~0.097) and postoperative foveal thickness (P=0.003, B=-0.439, 95%CI: -0.666~-0.213).

Conclusions : Vitrectomy is effective in closing laser-induced full-thickness MHs and improving visual acuity. Preoperative choroidal depression, worse preoperative VA, failed MH closure, greater postoperative EZ defect and thinner postoperative foveal thickness are predictive factors for worse final VA.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

 

Figure 1. Macular structures of patient No. 5 before and 6-months after surgery shown by SD-OCT. MH closed with continuous external limiting membrane (ELM) and focal disruption of ellipsoid zone (EZ).

Figure 1. Macular structures of patient No. 5 before and 6-months after surgery shown by SD-OCT. MH closed with continuous external limiting membrane (ELM) and focal disruption of ellipsoid zone (EZ).

 

Figure 2. Macular structures of patient No. 19 before and 6-months after surgery shown by SD-OCT. The patient had a subfoveal choroidal depression before surgery. MH closed with disruption of both the EZ and ELM.

Figure 2. Macular structures of patient No. 19 before and 6-months after surgery shown by SD-OCT. The patient had a subfoveal choroidal depression before surgery. MH closed with disruption of both the EZ and ELM.

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