Abstract
Purpose :
The purpose of this study is to describe the incidence and risk factors for idiopathic persistent post-operative anterior uveitis (IPPAU) after resident-performed cataract surgery.
Methods :
A multi-center, retrospective cohort study was conducted on all routine, elective, uncomplicated, resident-performed cataract surgeries between January 1, 2019 and January 1, 2021 across two different ophthalmology residency training programs: the Veterans Affairs (VA) TN Valley Healthcare Center in Nashville, TN, USA and the Department of Ophthalmology, Columbia University, New York, NY, USA. Exclusion criteria included use of pupillary expansion or capsular support device, prior history of uveitis, rheumatological condition, penetrating trauma, endophthalmitis, neovascular glaucoma, any previous intraocular surgery or procedure. Data were collected on patient age, self-reported race/ethnicity, gender, history of diabetes or primary open angle glaucoma, and cumulative dissipated energy (CDE) used in phacoemulsification. The primary outcome measure was incidence of IPPAU at the 3-month postoperative visit or later.
Results :
Of the 406 eyes that met inclusion criteria, 33 (8.1%) developed IPPAU. The incidence of IPPAU among patients of African American race was 14.5% (21 out of 145 eyes, relative risk [RR] 3.51; 95% confidence interval (CI), 1.68, 7.34, p<.001). Males experienced less IPPAU (9 out of 185 eyes, 4.9%) compared to females (24 out of 221, 10.9%, RR 0.420; 95% CI, 0.190, 0.927, p=0.028). The average age of patients with IPPAU was 68.2 years, compared to 71.7 years among those who did not develop IPPAU (Mean difference of -3.5 years; 95% CI, -6.6, -0.4, p=0.028).
Conclusions :
African American race, female gender, and younger age appear to be risk factors for IPPAU following routine uncomplicated resident-performed cataract surgery. The findings from this study align with the existing body of literature on this condition, indicating their relevance.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.