Abstract
Purpose :
Rhegmatogenous retinal detachment (RRD) is an important cause of blindness and visual impairment in adults, especially in young adults. High myopia is one of the most important risk factors causing RRD. China has a large population of myopia patient. As reported by NHC in 2020, the prevalence of myopia among college students in China has exceeded 90%, and the myopic complications is more severe in China. However, whether the increase of myopia population in China is accompanied by an increasing prevalence of RRD is still unknown, which lacks large sample and real-world data evidence.
Methods :
We calculated the annual incidence rates as new yearly RRD diagnoses divided by the total national population in 2016, 2017, 2018, 2019, 2020, 2021. Incidence age groups of 10-year increments, across provinces in mainland China (23 provinces, 5 autonomous regions, 4 municipalities) were analysed from the total annual population information provided by the National Bureau of Statistics of China and the incidence rate was adjusted for sex and age, using the weights from a reference population (2020 Chinese National Census). Poisson distributions was used to calculate 95% confidence intervals (CI). Measurement data are expressed as a median (interquartile range, IQR). Counts were catalogued in the form of number and proportion. P<0.05 was designated as statistically significant. Statistical analyses were calculated with edition R 4.3.1.
Results :
Form 2016-2021, a growing incidence of primary RRD was identified in China. In 2021, 90101 patients were primarily diagnosed with RRD (median [SD] age, 51 [15] years). The incidence rate was 4.04 per 100,000 person-years in 2021, (2.68 in 2016, 2.97 in 2017, 3.21 in 2018, 3.72 in 2019, 3.75 in 2020), which had increased by 51% over five years. In 4 age categories (20-29, 30-39, 40-49, 50-59) the incidence increased with years. RRD incidence was higher with male than female from 2016-2020 (4.49 per 100,000 person-years in male vs 3.55 per 100,000 person-years in female in 2021). The incidence rate of RRD varied in different province from 0.035 per 100,000 person-years in Tibet to 24.2 in Shanghai province.
Conclusions :
In this study, yearly increase of primary RRD incidence rates was observed in China from 2016-2020. A significant variation of incidence and trend of incidence change exhibit among province.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.