Abstract
Purpose :
To investigate the role of Selective Laser Trabeculoplasty (SLT) as an outcome predictor of trabecular meshwork (TM)-based microinvasive glaucoma surgery (MIGS).
Methods :
Twenty-nine patients who received SLT and subsequent TM-based MIGS with no other intervening glaucoma procedure at Massachusetts Eye and Ear were included. Qualified success (QS) was defined as IOP reduction ≥20% with 5 mmHg ≤ IOP ≤ 21 mmHg with ≤ baseline medications for at least two consecutive visits. SLT responder eyes maintained QS at POY1, while SLT non-responder eyes failed to maintain QS at POY1. A Kaplan-Meier (KM) curve assessed survival after MIGS among SLT responders versus SLT non-responders using the same QS criteria.
Results :
The cohort consisted of 29 patients of which 18 were SLT responders and 11 SLT non-responders. These two groups had similar baseline IOP and demographics aside from age (70.83 in SLT responders versus 64.45 in SLT non-responders, p=0.045). At POM6, 88% of SLT responder eyes successfully responded to subsequent MIGS versus only 67% among SLT non-responders (p=0.022). At POY1, 57% of SLT responder eyes maintained a MIGS response versus only 33% of SLT non-responder eyes that maintained a MIGS response (p=0.011).
Conclusions :
A successful 1-year response to SLT seems to predict a more favorable TM-based MIGS response at POM6 and POY1.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.