Abstract
Presentation Description :
The eye has specific optical and biomechanical properties that correspond to each other to ensure the quality of vision and the shape and elasticity of the eye. The interdependence of optical and mechanical parameters should be reflected in the modelling of eye tissues, but this imposes many limitations. Computational models of the human eye fall into two main groups. The first group consists of biomechanical models utilised to advance the understanding of the mechanical behaviour of the human eye under various physiological and pathological conditions. The second group consists of optical models used to analyse and predict how changes in eye biometrics affect the refraction and aberrations of the eye's optical system. It turns out that studying the interrelationship between the biomechanics, structure, and optical properties of eye components will enable the personalization of such models. It is possible to select a combination of material parameters of individual eye components, boundary conditions, and biometric data to ensure optical-mechanical (OM) integrity that compensates for physiological changes in intraocular pressure (IOP) without compromising image sharpness. This research assessed the results of numerical simulations for some factors such as geometry, different loading conditions, and material properties, and fine-tuned the OM characteristics of the eye's primary components to maintain the visual image quality (within the specified range of IOP levels). This enables the numerical simulation to lead to cost-effective results and increases its applicability in clinical practise. The proposed OM model can be upgraded with new functions, which can be a solid basis for future research on ocular biomechanics. The results of the current study may have implications both in the research and clinical areas for better perspectives and invaluable information for determining the mechanical properties of the eye.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.