Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Comparison of Descemet membrane endothelial keratoplasty (DMEK) with 3D heads-up display versus standard operating microscope
Author Affiliations & Notes
  • Johannes Schiefelbein
    Department of Ophthalmology, Ludwig-Maximilians-Universitat Munchen, Munich, Bayern, Germany
  • Franziska Kruse
    Department of Ophthalmology, Ludwig-Maximilians-Universitat Munchen, Munich, Bayern, Germany
  • Jakob Siedlecki
    Department of Ophthalmology, Ludwig-Maximilians-Universitat Munchen, Munich, Bayern, Germany
  • Siegfried Priglinger
    Department of Ophthalmology, Ludwig-Maximilians-Universitat Munchen, Munich, Bayern, Germany
  • Ben Asani
    Department of Ophthalmology, Ludwig-Maximilians-Universitat Munchen, Munich, Bayern, Germany
  • Footnotes
    Commercial Relationships   Johannes Schiefelbein Novartis, Code F (Financial Support); Franziska Kruse None; Jakob Siedlecki Bayer AG, Novartis Pharma GmbH, Pharm-Allergan GmbH, Code C (Consultant/Contractor), Carl Zeiss Meditec AG, Novartis Pharma GmbH, Bayer AG, Pharm-Allergan GmbH, Oculentis OSD Medical GmbH, Oertli AG, Code F (Financial Support); Siegfried Priglinger Abbott, Alcon, Geuder, Oculus, Schwind, STAAR, TearLab, Thieme Compliance, Ziemer, Zeiss, Code C (Consultant/Contractor), Abbott, Alcon, Hoya, Oculentis, Oculus, Schwind, Zeiss, Novartis, Code F (Financial Support); Ben Asani Novartis, Code F (Financial Support)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 1088. doi:
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      Johannes Schiefelbein, Franziska Kruse, Jakob Siedlecki, Siegfried Priglinger, Ben Asani; Comparison of Descemet membrane endothelial keratoplasty (DMEK) with 3D heads-up display versus standard operating microscope. Invest. Ophthalmol. Vis. Sci. 2024;65(7):1088.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess the efficacy and outcomes of Descemet membrane endothelial keratoplasty (DMEK) operated with a standard operating microscope (SOM) and a three-dimensional heads-up display (3D HUD).

Methods : Eighty-six eyes of 86 patients with corneal decompensation due to fuchs endothelial dystrophy (FED) or pseudophakic bullous keratopathy (PBK). All eyes underwent Descemet membrane endothelial keratoplasty (DMEK) using either a 3D HUD (NGENUITY; Alcon Inc., Fort Worth, Texas, USA; n=39 eyes) or a SOM setting (n=47 eyes); in cases of significant cataract, additional phacoemulsification with intraocular lens (IOL) implantation was performed. Minimum follow-up was three months.

Results : There were 39 eyes in the 3D HUD and 47 eyes in the SOM group. In general, the 3D HUD group was slightly younger than the SOM group (72.64±8.34 vs. 76.51±11.76, p=0.02). Both groups did not differ concerning their indication for DMEK (FED vs. PBK, p=0.83), other visual acuity limiting diseases (p=0.64), past keratoplasty procedure (p=0.37) and preoperative BCVA (p=0.09). Postoperatively, 3D HUD and SOM were comparable concerning the duration of surgery (3D HUD: 34.85±21.22 min; SOM: 41.21±24.38 min; p=0.09), the rate of surgical re-bubbling (17.9 % vs. 25.5 %; p=0.45), rate of graft rejection (5.1 % vs. 21.3 %) and final BCVA (0.30±0.34 vs. 0.35±0.34 logMAR; p=0.19).

Conclusions : On par results to a conventional operating microscope can be achieved with a 3D HUD setting when performing Descemet membrane endothelial keratoplasty including the duration of surgery, postoperative complications such as graft rejection and final BCVA.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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