Abstract
Purpose :
This study aims to translate, culturally adapt, and validate the Ocular Surface Disease Index into Spanish for the Mexican population.
Methods :
This was a cross-sectional observational study conducted in two phases. The first phase corresponded to the process of translation and cross-cultural adaptation of the OSDI into Spanish. A translation was carried out independently by a native English speaker, a bilingual ophthalmologist and a professional translator. Crawford and INFLESZ indexes were calculated. A cultural adaptation was conducted to ensure that the translated questionnaire was easily understandable by Mexican patients. Coherence, relevance, clarity and sufficiency were evaluated independently by an expert committee composed of 5 bilingual corneal specialists. A pilot was done to evaluate the items comprehension by the target population and ensure a correct cultural adaptation was achieved. The second phase involved the validation and metric analysis of the OSDI with patients. The internal consistency of the instrument was assessed using Cronbach’s alpha coefficient, an alpha >0.70 was considered to be acceptable. Test-retest reliability was evaluated by calculating the intraclass correlation coefficient values from the first and second entries.
Results :
A total of 372 participants were included in the study, 63.4% of whom were female, with an age range from 17 to 86 years. According to the INFLEZS readability index, symptom-related items achieved scores of 82.56, 72.69, 85.81, 73.24, and 74.24. Items related to lifestyle obtained scores of 71.39, 76.90, 58.27, and 72.56, while in the environmental domain, scores of 83.61, 74.03, and 58.93 were recorded. Using the Crawford index, symptom scores were 3.6, 4.6, 3.5, 4.1, and 3.8, lifestyle scores were 4.7, 4.1, 5.1, and 4.6, and environmental scores were 3.7, 4.4, and 5.7. The Cronbach's alpha coefficient was 0.868. Based on the scores from the OSDI questionnaire, patients were classified as having no dry eye (n=129), mild dry eye (n=99), moderate (n=45), and severe (n=99).
Conclusions :
This study developed and validated the Mexican version of the Ocular Surface Disease Index, assessing its reliability and internal consistency. With the aid of this tool, ophthalmologists and researchers will be able to assess and monitor Mexican-Spanish-speaking patients with dry eye in routine clinical practice and future research.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.