Abstract
Purpose :
Despite extensive research on strokes and ocular migraines individually, there remains a paucity of studies exploring a potential relationship between the two. This retrospective study delves into the intricate relationship between ocular migraine, stroke, and key comorbidities known to be risk factors for stroke across multiple patient demographics.
Methods :
The data was collected retrospectively from an EPIC EMR database through an IRB approved registry. Patient charts were screened for diagnosis of ocular migraine, stroke and comorbidities including: hypertension, smoking, diabetes, hyperlipidemia, atherosclerosis, heart failure, transient ischemic attacks (TIAs), and family history of stroke. Furthermore, they were categorized by sex, race, and age. A chi square test was performed to assess the association between ocular migraine and stroke.
Results :
Out of the 1,008,798 patient charts screened, 5,746 individuals were identified with ocular migraine (0.57%), while 14,171 patients had a stroke diagnosis (1.40%). Additionally, 218 patients had a history of both ocular migraine and stroke (0.02%). Within this subset, females exhibited the highest prevalence, constituting 82.57% of the cohort. Among racial demographics, Caucasians emerged as the most prevalent group, making up 83.49% of the total cases. Notably, patients aged 40-49 accounted for 22.94% of patients with both ocular migraine and stroke, with hypertension identified as the most common comorbidity (55.96%). A chi-square test of independence was performed to determine the association between ocular migraine and stroke (X2 = 238.18; p<0.00001).
Conclusions :
Our findings illuminate significant association between ocular migraine and stroke. Furthermore, the data presents distinct demographic patterns in patients with both ocular migraine and stroke. There is a higher prevalence among females, Caucasian populations, and patients from 40-49 years of age. In addition, hypertension was seen as the most prevalent comorbidity in patients diagnosed with both ocular migraine and stroke. These results provide a foundation for further research into the nuanced relationship between the two.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.