Anterior-posterior radius ratio of corneal curvature and keratometric index in children with congenital cataract.

Abstract

Purpose : To explore the anterior-posterior radius ratio of corneal curvature (AP ratio) and keratometric index in children with congenital cataract (CC), and to evaluate its accuracy in estimating the total and posterior cornea refractive power and calculating the intraocular lens power.

Methods : The simulated total, anterior, and posterior radius of corneal curvature and central corneal thickness were measured using swept-source optical coherence tomography (SS-OCT) in children with CC. The predicted refractive outcome using four different types of corneal refractive power was calculated using the optimized lens constants.

Results : We enrolled 73CC eyes (73children) and the 36contralateral normal eyes in monocular CC were used as the control group in this study. The mean AP ratio was 1.229±0.100and the mean keratometric index was 1.3281±0.0039. Except for central corneal thickness (CCT) (P=0.007), there was no significant difference in corneal parameters between the CC eyes and control group (P>0.05). Mean estimation errors of P_cal within±0.50 D were 90.4 % (66 eyes) compared with P_actual. Mean estimation error of PostP_cal within±0.50D was 89.0 % (65 eyes). The total corneal refractive power calculated with the mean keratometric index of 1.3281 had the lowest MAE, MedAE, ME and the highest percentage of eyes within 0.50 and 1.00D during different types of corneal refractive power except for the actual corneal refractive power.

Conclusions : The AP ratio and keratometric index obtained by SS-OCT could improve the prediction accuracies of the postoperative refraction of the CC. the CCT of CC eyes was thicker than that of contralateral healthy eyes.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.