Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Corneal Findings in Patients with Ophthalmology Consult for Candidemia
Author Affiliations & Notes
  • Radhika Gholap
    Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Bhakti Panchal
    Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Hyunjin Choi
    Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Ramya Swamy
    Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Jacqueline Bork
    Infectious Diseases, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Zachary Pek
    Infectious Diseases, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Wuqaas Wuqaas
    Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Kenneth Taubenslag
    Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States
  • Footnotes
    Commercial Relationships   Radhika Gholap None; Bhakti Panchal None; Hyunjin Choi None; Ramya Swamy None; Jacqueline Bork None; Zachary Pek None; Wuqaas Wuqaas None; Kenneth Taubenslag None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 2001. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Radhika Gholap, Bhakti Panchal, Hyunjin Choi, Ramya Swamy, Jacqueline Bork, Zachary Pek, Wuqaas Wuqaas, Kenneth Taubenslag; Corneal Findings in Patients with Ophthalmology Consult for Candidemia. Invest. Ophthalmol. Vis. Sci. 2024;65(7):2001.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : This study examines corneal fundings and interventions for inpatients hospitalized for candidemia. While there have been numerous studies focusing on the frequency of chorioretinal findings and endophthalmitis in patients with candidemia, there is little data on ocular surface pathology in these patients.

Methods : This is a single tertiary care retrospective cohort study with patients from 2017-2020. Inclusion criteria included candidemia and completed ophthalmologic consultation. Microbiologic data, ophthalmic exam findings and treatments, and visual outcomes were collected.

Results : 143 patients met inclusion criteria. 71 patients of 143 (49.65%) could not provide clinical history. 8.39% patients reported ocular pain or changes in vision. 26 patients (18%) had nonspecific retinal findings such as hemorrhage and cotton wool spots vs. chorioretinitis. No patients had candida endophthalmitis. Corneal findings in patients with candidemia included exposure keratopathy in 16.08% (n=23) and corneal ulcer in 2.10% (n=3) of patients. Lubrication (n=20) or topical antibiotics (n=8) and eyelid taping were recommended in 19.58% of patients.

Conclusions : This study found no cases of candida endophthalmitis. Corneal exposure was much more common than candida endophthalmitis, and several patients were diagnosed with vision threatening corneal ulcer. These findings highlight a need to build and refine protocols to mitigate corneal exposure in the intensive care unit. Given the prevalence of exposure keratopathy in this study, instituting protocols to fight corneal exposure may be as beneficial, if not more beneficial, than screening for ocular candidiasis itself.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×