Abstract
Purpose :
The goal of the study is to investigate the performance of an Extended Depth of Focus (EDoF) Scleral lens (SL), specifically designed for presbyopic patients with keratoconus (KC), by correcting the higher order aberrations (HOAs) and aligning the EDoF profile with the patient's line of sight.
Methods :
Two individuals (4 eyes) with KC and 2 individuals (4 eyes) with normal optics were included in this study. A diagnostic SL trial was done to obtain acceptable fit and centration, and the best corrected visual acuity (BCVA) with conventional optics was measured using logMAR. The customized SL was then made to correct the residual HOAs measured with the conventional SL and to induce the EDoF design. The EDoF design is based on a periodically varying add power profile across the pupil diameter. Both the HOA correction and the EDoF profile were offset based on the precise centration and rotation of the SL on the eye and the patient's line of sight, diverging from the conventional methods currently employed. A defocus curve was generated by measuring high (100%) and 50% contrast logMAR visual acuity (BCVA) at 6, 2, 1, 0.7, 0.5, and 0.4 m under typical photopic light conditions (309 LUX).
Results :
The mean age of KC and normal participants were 47 ± 5 years and 51.5 ± 9 years, respectively. The average mean K value for the KC and the normal individuals were 52 ± 5 D and 44 ± 1 D, respectively. The mean high contrast BCVA at 6, 2, 1, 0.7, 0.5, and 0.4 m was 0.01, 0.01, 0.06, 0.12, 0.19, and 0.23 logMAR, respectively, and low contrast VA was 0.14, 0.19, 0.16, 0.18, 0.26, and 0.32 logMAR, respectively, in the participants with KC. In normal participants, the mean high contrast VA was -0.06, -0.06, -0.04, 0.00, 0.08, and 0.25 logMAR, respectively, and low contrast VA was -0.04, 0.00, 0.03, 0.11, 0.22, and 0.38 logMAR, respectively.
Conclusions :
This preliminary study successfully demonstrated the effectiveness of integrating fully customized presbyopia correction approaches into a scleral lens in which individuals’ ocular optics and line of sight were considered. In conjunction with the new EDoF design, a significant improvement in visual acuity was found and this finding suggests the potential of personalized presbyopia correction in providing eyes with normal and abnormal optics with satisfactory depth of focus.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.