Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Novel retinal tracking device for neural response detection
Author Affiliations & Notes
  • Marta Katarzyna Skrok
    Faculty of Physics, Astronomy and Informatics, Uniwersytet Mikolaja Kopernika w Toruniu, Torun, Kujawsko-Pomorskie, Poland
  • Robert Konklewski-Pilewicz
    INOKO.VISION LLC, Poland
  • Patrycjusz Stremplewski
    Faculty of Physics, Astronomy and Informatics, Uniwersytet Mikolaja Kopernika w Toruniu, Torun, Kujawsko-Pomorskie, Poland
    INOKO.VISION LLC, Poland
  • Maciej Nowakowski
    INOKO.VISION LLC, Poland
  • Valentyna Pryhodiuk
    Faculty of Physics, Astronomy and Informatics, Uniwersytet Mikolaja Kopernika w Toruniu, Torun, Kujawsko-Pomorskie, Poland
  • Anna Szkulmowska
    INOKO.VISION LLC, Poland
  • Maciej Szkulmowski
    Faculty of Physics, Astronomy and Informatics, Uniwersytet Mikolaja Kopernika w Toruniu, Torun, Kujawsko-Pomorskie, Poland
  • Footnotes
    Commercial Relationships   Marta Skrok None; Robert Konklewski-Pilewicz None; Patrycjusz Stremplewski None; Maciej Nowakowski None; Valentyna Pryhodiuk None; Anna Szkulmowska None; Maciej Szkulmowski None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 3369. doi:
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      Marta Katarzyna Skrok, Robert Konklewski-Pilewicz, Patrycjusz Stremplewski, Maciej Nowakowski, Valentyna Pryhodiuk, Anna Szkulmowska, Maciej Szkulmowski; Novel retinal tracking device for neural response detection. Invest. Ophthalmol. Vis. Sci. 2024;65(7):3369.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Eye trackers using images of anterior eye features and light reflections from cornea and lens, widely used in eye movement research, require subject-dependent calibration with complex eye models, and are prone to errors caused by the dynamics of pupil and lens. As a result, are not accurate nor precise enough to reliably examine eyeglobe micro-movements. The purpose of this study was to register eye movements during various visual psychophysical tests with high accuracy and high precision using a retinal-based eye tracker prototype device that operates with high resolution and high speed.

Methods : Our retinal tracker device is based on an optical arrangement of a confocal scanning microscope optimized for retinal imaging. The accuracy and precision of the prototype were measured using an artificial eye and model trajectories given to the scanning system. Then, eye movement trajectories were recorded for 8 healthy subjects aged 25-45 during different visual tasks, including 15-second fixation, saccades up to 4 degrees, and smooth pursuit up to 30 deg/second. Additionally, pilot studies were performed on 4 volunteers, during which the trajectory of eye movements was recorded at 2-hour intervals for 24 hours.

Results : The prototype retinal eye tracker enables maximum precision from 0.03 to 2.4 arcmins (for drift and saccades), with an accuracy 0.02 to 0.1 degs (for saccades 0.25 and 4 degs). The device's calibration is subject-independent. Various psychophysical experiments can be performed due to the use of a scanning beam invisible to the human eye and a synchronized LCD screen that allows to display of any visual tasks created with PsychoPy software. The registered eye trajectories are segmented into microsaccades and drifts, followed by mathematical description of the basic parameters of these components. These parameters not only show individual differences but change in time due subject-dependent diurnal variability.

Conclusions : Our eye tracker can register eye movements during psychophysical tasks with accuracy and precision significantly exceeding that offered by commonly used corneal eye trackers. This allows following the evolution of characteristic eye trajectory patterns over time. Additionally, it is a safe and non-invasive device for the examined subject, what makes it beneficial for monitoring patients diagnosed with various diseases, including mental and neurodegenerative diseases.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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