Abstract
Purpose :
To evaluate the relationship between retinal microvascular changes analyzed by choriocapillaris vessel density (VD) obtained with swept-source optical coherence tomography (OCT) angiography and coronary calcium score obtained with coronary artery computed
tomography (CT).
Methods :
We evaluated the association between macular perfusion assessed by choriocapillaris flow void area measured with optical coherence tomography angiography (OCTA) and coronary calcium score acquired with coronary artery computed tomography (CT). The vessel density of the superficial capillary plexus (SCP) layers, deep capillary plexus layers (DCP), and choriocapillaris were quantitatively analyzed after image processing. Coronary artery calcium score was measured using Agatston method with coronary artery computed tomography (CT) scan.
Results :
Total 122 patients were included in the study. In the multivariate study, calcium score and age exhibited significant positive correlations with CAC scores (β =0.074 and 0.005; p = 0.011 and 0.001, respectively). Choriocapillaris flow void features acquired using OCTA were associated with Agatston score.
Conclusions :
OCTA can improve the risk assessment of coronary artery calcium score, and images produced by OCTA can be utilized as a predictive indicator of cardiovascular risk profile.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.