Abstract
Purpose :
To investigate the longitudinal changes of anterior ocular feature among slow and fast myopia progress young school children
Methods :
A sum of 121 children from first year of primary school was recruited in Shanghai, China. All children were examined at baseline and followed up for 2 years. All participants underwent comprehensive examinations including ocular biometric assessment and cycloplegic auto-refraction. Children were divided into two groups based on myopia progress in 2-year: group A (slow progress, <1.0D,N=145) and group B (fast progress, >1.0D,N=88). Detail anterior ocular biometric data information was compared between two groups.
Results :
In both groups, axial length elongated and anterior chamber depth (ACD) deepened considerably (P<0.001). Anterior corneal surface curvature flattened in both flat meridian and steep meridian in group A, while these parameters revealed steepen changes in group B. In terms of lens thickness (LT), it decreased statistically significance in group B from 3.60±0.20 mm to 3.45±0.17 mm (P<0.001), but showing no remarkable change in group A (3.58±0.18 mm to 3.49±0.18 mm, P=0.387). In contrast to lens thickness, an average tilt of lens in group A reduced from 5.21±1.26°to 4.95±1.23°with a P value of 0.043, while it presented no significant declination in group B from 5.14±1.43°to 4.89±1.29°(P=0.181). LT and ACD significantly correlated with spherical equivalent changes (P≤0.01).
Conclusions :
Slow and fast myopia progress children presented similar ACD deepen changes, but showed differences in corneal curvature and lens thickness change pattern.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.