Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Imaging and clinical analysis of macrophage-like cells in humans
Author Affiliations & Notes
  • Richard B Rosen
    Ophthalmology, New York Eye & Ear Infirmary, New York, New York, United States
    Icahn School of Medicine at Mount Sinai, New York, New York, United States
  • Footnotes
    Commercial Relationships   Richard Rosen Visionix- Optovue, Boehringer-Ingelheim, Lumithera, CellView, Regeneron, Code C (Consultant/Contractor), Ocusciences, Topcon, Canon, Code F (Financial Support), Guardion Health, CellView, Code O (Owner), Visionix- Optovue, Code P (Patent)
  • Footnotes
    Support  National Institutes of Health : R01EY027301, P30EY026877, R01EY031360, R01EY032147, R01EY032669
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4256. doi:
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      Richard B Rosen; Imaging and clinical analysis of macrophage-like cells in humans. Invest. Ophthalmol. Vis. Sci. 2024;65(7):4256.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Presentation Description : Clinical imaging of microglia and macrophages are the next frontier in assessing in vivo cellular activity in a variety of ocular pathologies. Recent advances in commercial OCT devices have enabled high resolution enface imaging capable of distinguishing key morphological features of resident immune cells (so called macrophage-like cells) at the vitreous-retinal interface. The speed and patient-friendly design of clinical OCT platforms along with the simplicity of post-imaging processing algorithms offer new opportunities for clinical studies of cellular dynamics across the gamut of disease entities. Processing techniques, clinical examples and preliminary studies will be presented.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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