Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Perfluorocarbon liquid use in Endoscopic Pars Plana Vitrectomy Compared to Microscopic Pars Plana Vitrectomy during Retinal Detachment Repair
Author Affiliations & Notes
  • Riya Parikh
    Department of Ophthalmology, The University of Kansas School of Medicine, Kansas City, Kansas, United States
  • Shreeya Dalla
    Department of Ophthalmology, The University of Kansas School of Medicine, Kansas City, Kansas, United States
  • Amanda Hertel
    Department of Ophthalmology, The University of Kansas School of Medicine, Kansas City, Kansas, United States
  • Matthew M Pfannenstiel
    Department of Ophthalmology, The University of Kansas School of Medicine, Kansas City, Kansas, United States
  • Radwan Ajlan
    Department of Ophthalmology, The University of Kansas School of Medicine, Kansas City, Kansas, United States
  • Footnotes
    Commercial Relationships   Riya Parikh None; Shreeya Dalla None; Amanda Hertel None; Matthew Pfannenstiel None; Radwan Ajlan None
  • Footnotes
    Support  National Center for Advancing Translational Sciences of the National Institutes of Health under the Award Number UL1TR002366.
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4040. doi:
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    • Get Citation

      Riya Parikh, Shreeya Dalla, Amanda Hertel, Matthew M Pfannenstiel, Radwan Ajlan; Perfluorocarbon liquid use in Endoscopic Pars Plana Vitrectomy Compared to Microscopic Pars Plana Vitrectomy during Retinal Detachment Repair. Invest. Ophthalmol. Vis. Sci. 2024;65(7):4040.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Retinal detachment (RD) is a serious vision threatening condition. Perfluorocarbon liquid (PFCL) can facilitate RD surgical repair, but endures extra cost and may cause unwanted complications. Endoscopic pars plana vitrectomy (EPPV) bypasses anterior segment opacity but requires the surgeon's hand holding the endoscope to remain stable for visualization compared to microscopic pars plana vitrectomy (MPPV), thus may result in frequent PFCL use during RD repair. The purpose of this study is to compare PFCL use rate between EPPV and MPPV for RD repair.

Methods : A retrospective chart review of 91 patients who underwent RD repair between August 2017 and July 2023 at a tertiary referral center was conducted. Inclusion criteria involved adult patients with RD repair who had a minimum 6-months post operative follow up visit. Patients' demographics and clinical data collection included visual acuity, intraocular pressure, intraoperative PFCL use, and surgical outcomes. Statistical analysis was performed with independent samples tests of proportion and a p-value of 0.05 was used. This study was approved by our institutional review board.

Results : Ninety-one patients met the inclusion criteria and were included in this study. The average age of patients was 58.1 ± 16 years (32 were females, 59 were males). There were 91 eyes that underwent RD repair, 44 eyes (48.3%) underwent EPPV and 47 eyes (51.6%) underwent PPV. In the EPPV group, 26 eyes (59%) had PFCL used during surgery (five eyes with rhegmatogenous retinal detachments [RRD], and 21 eyes with tractional retinal detachment [TRD]). In the MPPV group, 15 eyes (32%) had PFCL used during surgery (12 eyes with RRD, and three eyes with TRD). The rate of PFCL use between the EPPV and MPPV groups was statistically different (p=0.017). At one-month postoperative visit, the EPPV and PFCL subgroup had three retinal re-detachments (11.5%), while the MPPV and PFCL subgroup had one retinal re-detachment (6.7%).

Conclusions : In this study, PFCL use was significantly more frequent in the EPPV group compared to the MPPV group. When PFCL was used, there was no statistically significant difference in the re-detachment rate between both subgroups. PFCL may serve a larger role in EPPV that led to its increased use during RD repair. Prospective larger studies are needed to better evaluate the role of PFCL in EPPV for RD repair.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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