Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
SK-VFO test and widefield swept-source oct-guided selective vitrectomy (SV) for vitreous floaters and opacities (VFO)
Author Affiliations & Notes
  • Sebastian Eduardo Francis Stanga
    Stanga Ltd, London, United Kingdom
  • Andrea Saladino
    Stanga Ltd, London, United Kingdom
  • Ursula Reinstein
    Stanga Ltd, London, United Kingdom
  • John Marshall
    University College London, London, United Kingdom
    Stanga Ltd, London, United Kingdom
  • Timothy Archer
    Ophthalmology, London vision clinic, London, Please select, United Kingdom
  • Dan Reinstein
    Ophthalmology, London vision clinic, London, Please select, United Kingdom
  • Stuart William Harmer
    Stanga Ltd, London, United Kingdom
  • Paulo-Eduardo Stanga
    Stanga Ltd, London, United Kingdom
    University College London, London, United Kingdom
  • Footnotes
    Commercial Relationships   Sebastian Stanga None; Andrea Saladino None; Ursula Reinstein None; John Marshall None; Timothy Archer None; Dan Reinstein None; Stuart William Harmer None; Paulo-Eduardo Stanga None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4023. doi:
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      Sebastian Eduardo Francis Stanga, Andrea Saladino, Ursula Reinstein, John Marshall, Timothy Archer, Dan Reinstein, Stuart William Harmer, Paulo-Eduardo Stanga; SK-VFO test and widefield swept-source oct-guided selective vitrectomy (SV) for vitreous floaters and opacities (VFO). Invest. Ophthalmol. Vis. Sci. 2024;65(7):4023.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Describe the surgical technique of selective vitrectomy (SV) with removal of only core vitreous floaters and opacities (VFO). Present pre-and-post SV anatomical and functional results using a new testing methodology (SK-VFO Test) and two new and different navigated widefield swept-source OCT (SS-OCT) imaging technologies.

Methods : Retrospective study of 19 eyes (14 patients) with symptomatic VFO underwent the SK-VFO Test: logMAR best-corrected visual acuity (BCVA), SK infra-red confocal SLO (SK IRcSLO) (Canon Xephilio OCT-S1, Canon Medical Systems Europe, The Netherlands, Spectralis, Heidelberg Engineering, Germany) , straylight measurements (SM) (HD Analyzer, Keeler, USA), Light Disturbance Analyser (LDA, Binarytarget LDA, Portugal) and C-Quant (Oculus Optikgeräte GmbH, Germany) pre- and post-SV (25-G (n=4) or 27-G (n=15)).
Navigated multiwavelength ultrawidefield imaging with widefield swept-source OCT (SS-OCT) (Silverstone, Optos PLC, Scotland, United Kingdom) was performed pre- and post-SV to assess VFO, vitreoretinal interface (VRI)/posterior vitreous detachment (PVD) status obtaining 200° fundus images and 100 KHz 23 mm long SS-OCT scans with a 2.5mm imaging window. A new widefield SS-OCT technology allowing for 200 KHz 130° field-of-view single-scan 26mm long scans with a 12mm deep imaging window and a navigated imaging technique was also used pre- and post-SV in 4 eyes (DREAM OCT, Intalight, China).

Results : Post-SV, 93.75% of eyes experienced improvement in straylight measurements, 30% reduction in HD-analyser Objective Scattering Index, 58% reduction in LDA (p = 0.02) and 3% reduction in C-Quant log units. Both widefield SS-OCT technologies demonstrated the anatomical features of the pre-SV VFO, VRI/PVD status as well as the post-SV residual vitreous and VRI/PVD status (n=19 (100%)).

Conclusions : Selective Vitrectomy was effective in treating VFO. The SK-VFO Test showed post-SV resolution of VFO symptoms with resolution of VFO in UWF images and SS-OCT scans, improved visual function and improved light scatter results.
Navigated widefield SS-OCT is essential to assess pre- and post-SV VFO and vitreous characteristics. The new 200 KHz 26mm-long scan widefield SS-OCT technology, especially with a 12mm imaging window, allowed for significantly improved visualisation of the VFO, mid and cortical vitreous and VRI/PVD status pre- and post-SV.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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