Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Impact of systemic corticosteroids following scleral buckling repair of retinal detachment on surgical outcomes and pain management
Author Affiliations & Notes
  • Derrick James Wang
    Department of Ophthalmology and Visual Sciences, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
  • Cindy Chen
    Department of Ophthalmology and Visual Sciences, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
  • Thomas Allan Mendel
    Department of Ophthalmology and Visual Sciences, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
  • Footnotes
    Commercial Relationships   Derrick Wang None; Cindy Chen None; Thomas Mendel None
  • Footnotes
    Support  This work was funded by the Knights Templar Career Starter Grant, Ohio Lion’s Eye, Center for Clinical and Translational Science Path 2 K Award, and the NIH NEI Loan Repayment Program. Additional support came from the Research to Prevent Blindness New Chair Challenge Grant.
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 4011. doi:
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    • Get Citation

      Derrick James Wang, Cindy Chen, Thomas Allan Mendel; Impact of systemic corticosteroids following scleral buckling repair of retinal detachment on surgical outcomes and pain management. Invest. Ophthalmol. Vis. Sci. 2024;65(7):4011.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Scleral buckles (SB) often induce significant post-operative pain, which some physicians elect to treat with oral (PO) steroids. Given their proven ability to reduce inflammation and post-operative pain in other contexts, steroids can be an attractive option for medical management following surgical repair with SB. To our knowledge, no formal studies have investigated the utility of systemic steroids following SB surgery.

Methods : An IRB-approved retrospective chart review identified all patients at The Ohio State University Wexner Medical Center over a three-year period with retinal detachment (RD) repair involving SB use that were then split into PO steroid-receiving and non-receiving groups during the post-operative period. Patient demographics (age, gender, ethnicity, weight, diabetic status, pre-operative steroid use) and surgical detail (operative eye, primary SB status, SB element, reoperation status) were compared with χ2, Mann-Whitney U, and Fisher’s exact analyses. Additionally, visual acuity (VA), intraocular pressure (IOP), and reported pain across post-operative day one (POD1), week one (POW1), and month one (POM1) were compared.

Results : 41 (35%) of 116 identified patients underwent RD repair involving SB, of which eight (20%) received post-operative PO steroids. Four patients received them after POD1, four patients after POW1. A significant proportion of the steroid cohort was undergoing re-operation after previous vitrectomy for retinal detachment repair (75% versus 57%, p=0.048). The steroid and non-steroid groups showed no difference in pre-operative and POD1 VA, IOP, and reported discomfort. While a higher proportion of patients’ subsequent encounter notes mentioned pain at POW1 and POM1 (p=0.045 and p=0.011, respectively), six (75%) steroid recipients reported subjective improvement in eye pain after initiation.

Conclusions : This retrospective chart review identified a positive association between reoperation status and prescribed PO steroids after RD repair involving SB use. Despite noted ocular discomfort at follow-up visits, a majority of PO corticosteroid users experienced relief after utilization. Steroids did not affect VA and IOP during the immediate postoperative period. Given the retrospective nature of the study, future direction with prospective analysis will further clarify the role for adjunct systemic steroid use after SB.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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