Abstract
Purpose :
Recent wide-angle optical coherence tomography (W-OCT) can visualize wide-ranging and deep retinal and choroidal lesions. By using W-OCT, we investigated the retinal thickness and its effect on visual acuity in patients with retinal vasculitis.
Methods :
18 eyes of 11 people with retinal vasculitis which was detected by fundus fluorescein angiography, and those who underwent W-OCT from January 2020 to January 2023 were included. We measured foveal retinal and choroidal thickness using Xephilio OCT-S1. In addition, we created a central circle with a diameter of 3 mm centered on the fovea, an inner circle (3 mm to 10 mm), an intermediate circle (10 mm to 15 mm), and an outer circle (15 mm to 20 mm), and we measured average retinal thickness using the OCT Research Tool™. Those whose Log MAR visual acuity was better than 0 were defined as a good visual acuity group, and the others were defined as a poor visual acuity group, then we compared these groups using several parameters.
Results :
There were 12 eyes in the good visual acuity group and 6 eyes in the poor visual acuity group. Age of patients was 47.69±21.93 years old in good visual acuity group and 78.5±9.63 years old in the poor visual acuity group, there was significant difference (p=0.005). Foveal retinal thickness was 314.17 ± 52.8 μm in good visual acuity group and 295.33 ± 89.52 μm in the poor visual acuity group, there was no significant difference(p=0.58). But peripheral retinal thickness was significantly thicker in the good visual acuity group in the central, inner, middle, and outer circles (p=0.001, p=0.001, p=0.003, p=0.002).
Axial length was 24.26 ± 0.61 mm in the good visual acuity group and 25.0 ± 0.11 mm in the poor visual acuity group, with no significant difference (p = 0.101).
Conclusions :
The peripheral retinal thickness was significantly thicker in the good visual acuity group in retinal vasculitis patients. It is considered that in good visual acuity group, the peripheral retinal blood vessels had less inflammation and were less affected by ischemia, then the retinal thickness might be maintained.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.