Abstract
Purpose :
The purpose of this study was to evaluate the features of choroidal circulation in normal population and explore their relations with different factors by using ultra-wide field swept-source optical coherence tomography angiography (UWF SS-OCTA).
Methods :
252 eyes with 128 right eyes and 124 left eyes from 131 volunteers were included in this cross-sectional study. Choroidal vascularity index (CVI) and choroidal vascular volume per area (CVV/a or CVV) of Choroidal Sattler’s and Haller’s layer (CSHL) were estimated using images obtained from UWF SS-OCTA. The correlation of CVI and CVV with age, axial length (AL) and body mass index (BMI) were analyzed.
Results :
Among the individuals involved, the CVV was 76.76 ± 2.19 μm of the right eyes and 80.49 ± 3.10 μm of the left eyes; CVI was 30.82 ± 0.28% of the right eyes and 31.16 ± 0.34% of left eyes, respectively. The mean coefficient of variation of CVV was 0.30 ± 0.01 of the right eyes and 0.31 ± 0.01 of the left eyes; however, CVI was 0.15 ± 0.01 of the right eyes and 0.15 ± 0.01 of the left eyes. Higher CVI and CVV was associated with younger age. The overall association between CVI or CVV and AL or BMI was not statistially significant. However, decreased circulation of the CSHL can have been found with longer AL and higher BMI in specific subfields.
Conclusions :
CVI can be more stable parameter for describing CSHL’s circulation compared to CVV. Aging was associated with attenuated CSHL’s circulation. Taken together, these finding may be helpful and referential for retinal specialists to reveal risk factors of choroidal diseases.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.