Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
A new photochromic lens improves contrast sensitivity during fade-back
Author Affiliations & Notes
  • Raul Duarte-Toledo
    Laboratorio de Óptica, Universidad de Murcia, Murcia, Murcia, Spain
  • Juan Mompeán
    Laboratorio de Óptica, Universidad de Murcia, Murcia, Murcia, Spain
  • Alba M. Paniagua-Diaz
    Laboratorio de Óptica, Universidad de Murcia, Murcia, Murcia, Spain
  • Guillermo Perez
    Research & Development, Transitions Optical Limited (part of EssilorLuxottica), Tuam, Ireland
  • Emmanuel Kobia-Acquah
    Research & Development, Transitions Optical Limited (part of EssilorLuxottica), Tuam, Ireland
  • Nacer Lakhchaf
    Research & Development, Transitions Optical Limited (part of EssilorLuxottica), Tuam, Ireland
  • Daniel Parker
    Research & Development, Transitions Optical Limited (part of EssilorLuxottica), Tuam, Ireland
  • Coralie Barrau
    Research & Development, Transitions Optical Limited (part of EssilorLuxottica), Tuam, Ireland
  • Pablo Artal
    Laboratorio de Óptica, Universidad de Murcia, Murcia, Murcia, Spain
  • Footnotes
    Commercial Relationships   Raul Duarte-Toledo None; Juan Mompeán None; Alba Paniagua-Diaz None; Guillermo Perez Transitions Optical Limited, Code E (Employment); Emmanuel Kobia-Acquah Transitions Optical Limited, Code E (Employment); Nacer Lakhchaf Transitions Optical Limited, Code E (Employment); Daniel Parker Transitions Optical Limited, Code E (Employment); Coralie Barrau Transitions Optical Limited, Code E (Employment); Pablo Artal None
  • Footnotes
    Support  Agencia estatal de Investigacion, Spain (grant: PID2019-105684RB- I00/AEI/10.13039/50110001103)
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 6361. doi:
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      Raul Duarte-Toledo, Juan Mompeán, Alba M. Paniagua-Diaz, Guillermo Perez, Emmanuel Kobia-Acquah, Nacer Lakhchaf, Daniel Parker, Coralie Barrau, Pablo Artal; A new photochromic lens improves contrast sensitivity during fade-back. Invest. Ophthalmol. Vis. Sci. 2024;65(7):6361.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Photochromic lenses have been thoroughly assessed for its benefits in providing protection against light and glare when moving from a dark to a bright environment. Conversely, there has been limited research on visual performance during the fade-back phase in the transition from a bright to a darker environment. Here, we compared contrast sensitivity (CS) with two types of photochromic lenses during their fade back.

Methods : Ten healthy subjects (29.5±4.01 years old) were pre-trained to control the contrast of a sinusodidal grating projected in a calibrated display at central fixation, with a spatial frequency of 23 c/deg. Two photochromic lens prototypes, TO_1 [newly designed] and TO_2 [previous generation], with different fade-back speeds were used. The lenses were fully activated beforehand and then placed in front of the participant’s eye. Each subject was tasked to adjust the contrast of the grating to maintain the detection of the test while the photochromic lens was fading back. The required contrast was dynamically recorded every 2 seconds over 176 seconds, while the lens was changing from dark to its clear state. Three repeats were performed for each subject. The improvement in CS was computed with respect to the initial value with the photochromic lens in its darkest state. MANOVA with Tukey tests were used for statistical analysis.

Results : Overall, CS improvement was significantly better with TO_1 compared with TO_2 (p< 0.001). The greatest difference in CS improvement was observed between 30 to 60s during fade-back, with the cumulative CS improvement being 37% higher with TO_1 than TO_2 (p < 0.001). TO_1 (24 seconds) was 1.6 times faster in recovering 50% of optimal CS than TO_2 (38 seconds) during fade-back.

Conclusions : A newly designed, faster to fade-back, photochromic lens provides a faster improvement of visual performance when measured by changes in CS at high spatial frequencies. CS is fundamental to natural visual processing and an important tool for characterizing visual function, this new methodology is valuable to identify types of photochromic lenses that can maximize visual performance during fade-back while minimizing light stress.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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