Abstract
Purpose :
The risk of decreased contrast sensitivity (CS) after implantation of diffractive extended depth-of-focus (EDF) intraocular lenses (IOLs) is a concern in glaucomatous eyes; however, the factors involved have not been clarified. We prospectively compared the visual function of the eyes with primary open angle glaucoma (POAG) with EDF and monofocal IOLs. Therefore, the influence of perimetry on the visual acuity and CS was compared.
Methods :
EDF (ZXR00V, ZXV150-375: J&J) and monofocal (ZCB00V and ZCV150-375; J&J) IOLs were implanted into the eyes of 22 and 24 POAG eyes that were controlled with eye drops and with no central defect in visual field, respectively. Preoperatively and 3-months postoperatively, the mean deviation (MD), foveal sensitivity (FS), and the means of the central 4 points (central MD and central FS) were evaluated using standard 30-2 perimetry. Postoperative corrected distance visual acuity (CDVA) and photopic CS (CSV-1000) at 3, 6, 12, and 18 cycles/degree (cpd) were measured, and the influence of the perimetric indexes was evaluated through linear regression and stepwise multiple regression analyses.
Results :
In the linear regression analysis, no association was observed in CDVA in the eyes with both IOLs. Significant correlations were observed with most indexes in CS at 12 and 18 cpd of eyes with EDF IOLs (P < 0.044). The association between MD with CS 3 cpd (P < 0.046) and FS and CS at 18 cpd (P = 0.018) was significant of eyes with monofocal IOLs. Stepwise multiple regression revealed that the central FS was a dominant factor for a decrease of CS at 12 and 18 cpd.
Conclusions :
In the eyes with EDF IOLs, CS at higher spatial frequency was influenced by perimetry indexes, which differed from that of eyes with monofocal IOLs. Therefore, we hypothesize that reduced CS is inherent from EDF IOL implantations.
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.