Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Comparison of higher order aberrations in eyes with crystalline lenses and monofocal intraocular lenses
Author Affiliations & Notes
  • Andreas Hartwig
    Hartwig Research Center UG, Germany
  • Nicole Stuebiger
    Universitatsklinikum Hamburg-Eppendorf, Hamburg, Hamburg, Germany
  • Footnotes
    Commercial Relationships   Andreas Hartwig None; Nicole Stuebiger None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 6329. doi:
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      Andreas Hartwig, Nicole Stuebiger; Comparison of higher order aberrations in eyes with crystalline lenses and monofocal intraocular lenses. Invest. Ophthalmol. Vis. Sci. 2024;65(7):6329.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Implantations of intraocular lenses (IOLs) is currently the standard of care for patients with cataract. The objective of this study was to investigate the magnitude of higher order aberrations (HOAs) in eyes with either crystalline lenses or monofocal IOLs through clinical data.

Methods : Higher order aberrations were routinely measured in patients that attended the clinic for a refraction. A total of 36 patients comprising 72 eyes were included in the study. In 18 patients crystalline lenses were implanted and in 18 patients IOLS were implanted at least four weeks prior to the measurements. Measurements were performed using the i.Profiler (Carl Zeiss Vision, Aalen, Germany). Four consecutive measurements were taken for each eye and average by the internal software automatically. Higher order root-mean square (HO RMS) values were used for the comparison between the two groups, as the value is a representation of all higher order aberrations. Right eye data and differences between both eyes are presented. Mean values are reported in conjunction with standard deviations. All pupils were scaled to 3 mm.

Results : The mean age of the patients with crystalline lenses was 76±7 years, ranging from 68 to 89 years. Patients with monofocal IOLs were on average 80±6 years old, ranging from 68 to 93 years.
HO RMS for right eyes with crystalline lenses were 0.237±0.129 µm and 0.193±0.102 for eyes with IOLs. The range for crystalline lens eyes was from 0.089 to 0.580 µm and 0.083 to 0.434 µm for eyes with IOLs. The mean difference in spherical equivalence between right and left eyes was -0.42±1.36 D for eyes with crystalline lenses and 0.02±0.90 D. The mean difference for HO RMS between right and left eyes was -0.02±0.17 µm for crystalline lens eyes and -0.03±0.16 for IOL eyes.

Conclusions : A similar distribution of higher order aberrations was observed between the two groups. As mean HO RMS was lower for eyes with IOLs in situ. The mean difference was comparable between both groups. The mean difference in terms of spherical equivalent was reduced in eyes with IOLs.
The details indicate a good technical performance of monofocal IOLs in terms of HO RMS, which is a better representation of the visual experience than analysing specific Zernike coefficients.
IOLs implanted are not specified and therefore the presented data do not represented a particular IOL, but provide a general overview.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

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