Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 7
June 2024
Volume 65, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2024
Aqueous humor: a proximal organ liquid biopsy for ocular tumors - extending to new diseases and indications
Jesse L Berry
Author Affiliations & Notes
  • Jesse L Berry
    Children's Hospital Los Angeles, Los Angeles, California, United States
    University of Southern California, Los Angeles, California, United States
  • Footnotes
    Commercial Relationships   Jesse Berry World Care Clinical (DARC imaging), Code C (Consultant/Contractor), Aqueous humor cell free DNA for diagnostic and Prognostic evaluation of Ophthalmic Disease Pending 17/045,435 filed October 5, 2020 SLW 2771.008US1 (Berry, Xu, Hicks), Code P (Patent), DNA methylation signature of Retinoblastoma Provisional 63/375,511 filed September 13, 2022 (Berry, Xu, Liang, Li), Code P (Patent), Diagnostic Aqueous Humor Proteome Predicts metastatic potential in uveal melanoma Provisional 63/448,848 filed Feb 28, 2023 (Berry, Xu, Peng), Code P (Patent)
  • Footnotes
    Support  National Cancer Institute of the National Institute of Health Award Number R01CA282759 The Wright Foundation Children’s Oncology Group/ St. Baldrick’s Foundation Alex’s Lemonade Stand Foundation Grant # is 23-27881 Research to Prevent Blindness Medical Student Eye Research Fellowship (Recipient: Shreya Sirivolu, Mentor: Jesse Berry) Danhakl Family Foundation The Knights Templar Eye Foundation A. Linn Murphree, MD, Chair in Ocular Oncology The Berle & Lucy Adams Chair in Cancer Research The Larry and Celia Moh Foundation
Investigative Ophthalmology & Visual Science June 2024, Vol.65, 966. doi:
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      Jesse L Berry; Aqueous humor: a proximal organ liquid biopsy for ocular tumors - extending to new diseases and indications. Invest. Ophthalmol. Vis. Sci. 2024;65(7):966.

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Abstract

Presentation Description : The collaboration between MD/clinician - clincian/scientist and PhD scientist in the development of the aqueous humor for ocular tumors will be discussed. Within this collaboration there will be a focus on the disease applications ranging from pediatric retinoblastoma to adult uveal melanoma and new clinical indications such a molecular diagnostics, prognostics and detection of minimal residual (intraocular) disease. This companion talk with Liya Xu, PhD with discuss new disease and indications of the liquid biopsy platform while she will discuss the evolving role of various analytes.

This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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Copyright © 2025 Association for Research in Vision and Ophthalmology.
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