Abstract
Purpose :
This study aims to evaluate the effectiveness of pars plana vitrectomy with subsequent "medium-term" perfluoro-n-octane (PFO) in managing recurrent inferior retinal detachment complicated by Grade C-D proliferative vitreoretinopathy (PVR)
Methods :
We conducted a retrospective analysis on a consecutive series of patients presenting with recurrent inferior retinal detachment and Grade C-D PVR. Each patient underwent a 23-gauge pars plana vitrectomy, followed by a postoperative PFO for a duration of 2 months. Following this, all patients had the PFO removed in a carefully planned, staged procedure.
Results :
The study encompassed 38 eyes of 38 patients. The mean follow-up duration for these patients was 18.2 ± 6.92 months. Successful retinal reattachment was achieved in 92% of the cases (35 out of 38). Notably, the rates of reattachment were statistically equivalent, irrespective of whether the patients had undergone previous scleral buckle surgery. The primary reasons for redetachment in the remaining cases included hypotony with recurrent inferior PVR In addition to these outcomes, temporary elevation of intraocular pressure observed in 16% of the patients, and transient ocular inflammation noted in 12% of the cases. Further analysis revealed that two factors, specifically the macula-off status at the time of surgery (P = 0.02) and the persistent elevation of intraocular pressure (P = 0.02), were associated with poorer visual outcomes post-treatment.
Conclusions :
The application of medium-term PFO following pars plana vitrectomy emerges as a viable and effective technique for the operative management of patients with recurrent inferior retinal detachments complicated by Grade C-D PVR. It is noteworthy that the primary method of retinal repair, whether through scleral buckle or pars plana vitrectomy, did not significantly influence the rates of retinal reattachment. However, potential complications associated with this technique, particularly transient inflammation and elevation in intraocular pressure, warrant attention and careful patient monitoring and management in the postoperative period
This abstract was presented at the 2024 ARVO Annual Meeting, held in Seattle, WA, May 5-9, 2024.