Investigative Ophthalmology & Visual Science Cover Image for Volume 65, Issue 9
July 2024
Volume 65, Issue 9
Open Access
ARVO Imaging in the Eye Conference Abstract  |   July 2024
Real-World Performance Evaluation of an AI Model for Detecting Retinal Detachment in UWF Fundus Images
Author Affiliations & Notes
  • Hitoshi Tabuchi
    Technology and Design Thinking for Medicne, Hiroshima University, Hiroshima, Hiroshima, Japan
  • Justin Engelmann
    The University of Edinburgh., United Kingdom
  • Hodaka Deguchi
    Tsukazaki Hospital, Japan
  • Naofumi Ishitobi
    Tsukazaki Hospital, Japan
  • Miguel Bernabeu
    The University of Edinburgh., United Kingdom
  • Footnotes
    Commercial Relationships   Hitoshi Tabuchi, None; Justin Engelmann, None; Hodaka Deguchi, None; Naofumi Ishitobi, None; Miguel Bernabeu, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2024, Vol.65, PB0029. doi:
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      Hitoshi Tabuchi, Justin Engelmann, Hodaka Deguchi, Naofumi Ishitobi, Miguel Bernabeu; Real-World Performance Evaluation of an AI Model for Detecting Retinal Detachment in UWF Fundus Images. Invest. Ophthalmol. Vis. Sci. 2024;65(9):PB0029.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the retinal detachment identification performance of an AI model for Ultra-Wide Field (UWF) fundus cameras using real clinical data.

Methods : A retinal detachment identification model (AI model) was created using UWF retinal detachment and normal images collected at Tsukazaki Hospital Ophthalmology. To evaluate the performance of this model, an evaluation dataset representing a hypothetical real-world deployment scenario with an underlying disease prevalence of 0.1% was created. This dataset consisted of 30 UWF images of 30 eyes that underwent retinal detachment surgery (retinal detachment cases) and 2,970 UWF images of 2,970 normal eyes determined to be normal at a health screening center. The number of misses by the AI model was assessed at five levels, from 0 to 4 missed cases. The positive predictive value (PPV) was calculated based on predicted identification values for each level.

Results : With 0 misses (sensitivity 100%), the PPV was 1.1%; with one miss (sensitivity 96.7%) the PPV was 2.1%; with two misses (sensitivity 93.3%) the PPV was 2.3%; with three misses (sensitivity 90%) the PPV was 4.2%; and with four misses (sensitivity 86.7%) the PPV was 44.8%.

Conclusions : The realistic performance of the retinal detachment identification model developed here for real-world deployment is considered to have a sensitivity of 86.7%.

This abstract was presented at the 2024 ARVO Imaging in the Eye Conference, held in Seattle, WA, May 4, 2024.

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