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Anatomy and Pathology/Oncology

Production and Localization of Muc4/Sialomucin Complex and Its Receptor Tyrosine Kinase ErbB2 in the Rat Lacrimal Gland Free
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Maria E. Arango; Peter Li; Masanobu Komatsu; Carlos Montes; Coralie A. Carothers Carraway; Kermit L. Carraway
Tags: genes, erbb-2, lacrimal gland, receptor protein-tyrosine kinases, receptor, erbb-2, sialomucins
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2749-2756. doi:

Biochemistry and Molecular Biology

Null Missense ABCR (ABCA4) Mutations in a Family with Stargardt Disease and Retinitis Pigmentosa Free
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Noah F. Shroyer; Richard Alan Lewis; Alexander N. Yatsenko; James R. Lupski
Tags: family, mutation, retinitis pigmentosa, stargardt's disease, alleles
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2757-2761. doi:
A Novel Mutation in the M1S1 Gene Responsible for Gelatinous Droplike Corneal Dystrophy Free
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Gunnar Tasa; Jaak Kals; Kai Muru; Erkki Juronen; Andres Piirsoo; Siiri Veromann; Silvi Jänes; Aavo-Valdur Mikelsaar; Aavo Lang
Tags: genes, hereditary corneal dystrophy, mutation, nucleotides
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2762-2764. doi:

Clinical and Epidemiologic Research

New Visual Acuity Chart for Patients with Macular Hole Free
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Masayuki Horiguchi; Hiromitsu Suzuki; Yoshihisa Kojima; Yoshiaki Shimada
Tags: macular holes, visual acuity
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2765-2768. doi:

Cornea

Inhibitory Effect of a Complementary Peptide on Ulceration in the Alkali-Injured Rabbit Cornea Free
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Jeffrey L. Haddox; Roswell R. Pfister; Charnell I. Sommers; J. Edward Blalock; Matteo Villain
Tags: alkalies, cornea, neutrophils, oryctolagus cuniculus, peptides
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2769-2775. doi:
Characterization of Human and Mouse Angiopoietin-like Factor CDT6 Promoters Free
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Janice J. Liu; Steven E. Wilson
Tags: mice, oncogenes, angiopoietins, genes, transcription initiation site
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2776-2783. doi:
Corneal Endothelial Integrity in Mice Lacking Extracellular Superoxide Dismutase Free
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Anders Behndig; Kurt Karlsson; Thomas Brännström; Marie-Louise Sentman; Stefan L. Marklund
Tags: cornea, endothelium, mice, superoxide dismutase, superoxides
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2784-2788. doi:
Neuronal Nitric Oxide Synthase and the Autonomic Innervation of the Mouse Lacrimal Gland Free
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Chuanqing Ding; Benjamin Walcott; Kent T. Keyser
Tags: autonomic nervous system, lacrimal gland, mice, nerve supply, nitric oxide synthase
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2789-2794. doi:
Proinflammatory Chemokine Induction in Keratocytes and Inflammatory Cell Infiltration into the Cornea Free
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Jong-Wook Hong; Janice J. Liu; Jong-Soo Lee; Rahul R. Mohan; Rajiv R. Mohan; David J. Woods; Yu-Guang He; Steven E. Wilson
Tags: chemokines, cornea, cytokine, fibroblasts, inflammation
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2795-2803. doi:
Proliferation Rate of Rabbit Corneal Epithelium during Overnight Rigid Contact Lens Wear Free
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Patrick M. Ladage; Kazuaki Yamamoto; David H. Ren; Ling Li; James V. Jester; W. Matthew Petroll; Jan P. G. Bergmanson; H. Dwight Cavanagh
Tags: bromodeoxyuridine, contact lenses, cornea, corneal epithelium, muscle rigidity
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2804-2812. doi:
Tear Exchange under Hydrogel Contact Lenses: Methodological Considerations Free
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Jerry R. Paugh; Fiona Stapleton; Lisa Keay; Arthur Ho
Tags: contact lenses, hydrogel, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2813-2820. doi:

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Increased Binocular Enhancement of Contrast Sensitivity and Reduced Stereoacuity in Duane Syndrome Free
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Wendy E. Marshman; Emma Dawson; Majella M. Neveu; Michael J. Morgan; John J. Sloper
Tags: contrast sensitivity, duane retraction syndrome, eye
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2821-2825. doi:
Reduced Binocular Beat Visual Evoked Responses and Stereoacuity in Patients with Duane Syndrome Free
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John J. Sloper; Carolyn Garnham; Petrous Gous; Roger Dyason; Deborah Plunkett
Tags: duane retraction syndrome, evoked potentials, visual
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2826-2830. doi:

Glaucoma

Involvement of Protein Kinase C in TNFα Regulation of Trabecular Matrix Metalloproteinases and TIMPs Free
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J. Preston Alexander; Ted S. Acott
Tags: matrix metalloproteinases, protein isoforms, protein kinase c, regulation, tissue inhibitor of metalloproteinases
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2831-2838. doi:
Lack of Long-Term Drift in Timolol’s Effectiveness in Patients with Ocular Hypertension Free
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Boel Bengtsson; Anders Heijl
Tags: intraocular pressure, ocular hypertension, placebos, timolol, follow-up
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2839-2842. doi:
Optic Cup Enlargement Followed by Reduced Optic Nerve Head Circulation after Optic Nerve Stimulation Free
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Tetsuya Sugiyama; Hideaki Hara; Hidehiro Oku; Shunji Nakatsuji; Takashi Okuno; Masaaki Sasaoka; Takashi Ota; Tsunehiko Ikeda
Tags: hypertrophy, optic cup, optic disk, optic nerve, electric stimulation
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2843-2848. doi:
Neuroprotection of Retinal Ganglion Cells by Brimonidine in Rats with Laser-Induced Chronic Ocular Hypertension Free
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Elizabeth WoldeMussie; Guadalupe Ruiz; Mercy Wijono; Larry A. Wheeler
Tags: brimonidine, intraocular pressure, lasers, ocular hypertension, rats
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2849-2855. doi:
Stromelysin Gene Transfer into Cultured Human Trabecular Cells and Rat Trabecular Meshwork In Vivo Free
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Changwon Kee; Seongsoo Sohn; Jeong-Min Hwang
Tags: gene transfer techniques, stromelysin 1, trabecular meshwork
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2856-2860. doi:

Immunology and Microbiology

Cell Adhesion Molecule Expression in Cultured Human Iris Endothelial Cells Free
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Matthew D. Silverman; David O. Zamora; Yuzhen Pan; Paul V. Texeira; Stephen R. Planck; James T. Rosenbaum
Tags: cell adhesion molecules, endothelial cells, iris, intercellular adhesion molecule 1, proteins
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2861-2866. doi:
The Expression of Functional LPS Receptor Proteins CD14 And Toll-Like Receptor 4 in Human Corneal Cells Free
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Peter I. Song; Tonya A. Abraham; Youngmin Park; Adam S. Zivony; Brad Harten; Henry F. Edelhauser; Sherry L. Ward; Cheryl A. Armstrong; John C. Ansel
Tags: cd14 antigen, toll-like receptor 4, cornea, rna, messenger, proteins
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2867-2877. doi:
Acute Rejection of Orthotopic Corneal Xenografts in Mice Depends on CD4+ T Cells and Self-Antigen–Presenting Cells Free
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Kazumi Tanaka; Koh-hei Sonoda; J. Wayne Streilein
Tags: cornea, mice, rejection (psychology), t-lymphocytes, transplantation, heterologous
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2878-2884. doi:
Effect of Steroids on Acanthamoeba Cysts and Trophozoites Free
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Kathy McClellan; Kevin Howard; Jerry Y. Niederkorn; Hassan Alizadeh
Tags: acanthamoeba, cysts, dexamethasone, steroids, trophozoite
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2885-2893. doi:
Expression of CC Chemokines and Their Receptors in the Eye in Autoimmune Anterior Uveitis Associated with EAE Free
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Grazyna Adamus; Maria Manczak; Michal Machnicki
Tags: autoimmune diseases, beta-chemokines, chemokines, eye, monocyte chemoattractant protein-1
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2894-2903. doi:
Staphylococcus Corneal Virulence in a New Topical Model of Infection Free
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Emma B. H. Hume; Joseph J. Dajcs; Judy M. Moreau; Gregory D. Sloop; Mark D. P. Willcox; Richard J. O’Callaghan
Tags: contact lenses, cornea, infections, staphylococcus, virulence
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2904-2908. doi:

Lens

Characterization of a New, Dominant V124E Mutation in the Mouse αA-Crystallin–Encoding Gene Free
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Jochen Graw; Jana Löster; Dian Soewarto; Helmut Fuchs; Birgit Meyer; André Reis; Eckhard Wolf; Rudi Balling; Martin Hrabé de Angelis
Tags: crystallins, genes, mice, mutation, lens, crystalline
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2909-2915. doi:
Prenatal Lens Development in Connexin43 and Connexin50 Double Knockout Mice Free
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Thomas W. White; Caterina Sellitto; David L. Paul; Daniel A. Goodenough
Tags: connexin 43, gap junction protein, lens (device), lens, crystalline, mice
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2916-2923. doi:
αB-Crystallin in Lens Development and Muscle Integrity: A Gene Knockout Approach Free
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James P. Brady; Donita L. Garland; D. Earl Green; Ernst R. Tamm; Frank J. Giblin; Eric F. Wawrousek
Tags: crystallins, lens (device), lens, crystalline, mice, mice, knockout
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2924-2934. doi:
Lens Epithelium-Derived Growth Factor: Increased Survival and Decreased DNA Breakage of Human RPE Cells Induced by Oxidative Stress Free
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Hironori Matsui; Li-Ren Lin; Dhirendra P. Singh; Toshimichi Shinohara; Venkat N. Reddy
Tags: dna, growth factor, oxidative stress, retinal pigment cell, lens (device)
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2935-2941. doi:

Physiology and Pharmacology

Culture Model of Human Corneal Epithelium for Prediction of Ocular Drug Absorption Free
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Elisa Toropainen; Veli-Pekka Ranta; Anu Talvitie; Pekka Suhonen; Arto Urtti
Tags: cell culture techniques, cornea, corneal epithelium, drug absorption, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2942-2948. doi:
Effect of Endothelin and BQ123 on Ocular Blood Flow Parameters in Healthy Subjects Free
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Kaija Polak; Vanessa Petternel; Alexandra Luksch; Joachim Krohn; Oliver Findl; Elzbieta Polska; Leopold Schmetterer
Tags: choroid, endothelin-1, endothelins, optic disk, placebos
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2949-2956. doi:
Effects of Topical Latanoprost on Optic Nerve Head Circulation in Rabbits, Monkeys, and Humans Free
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Kiyoshi Ishii; Atsuo Tomidokoro; Miyuki Nagahara; Yasuhiro Tamaki; Mikiko Kanno; Yasuhiro Fukaya; Makoto Araie
Tags: cercopithecidae, latanoprost, optic disk, oryctolagus cuniculus, eye
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2957-2963. doi:

Retina

Correction of Early Subnormal Superior Hemiretinal ΔPO2 Predicts Therapeutic Efficacy in Experimental Diabetic Retinopathy Free
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Bruce A. Berkowitz; Yasuki Ito; Timothy S. Kern; Christopher McDonald; Roberta Hawkins
Tags: diabetes mellitus, diabetic retinopathy, magnetic resonance imaging, rats, alveolar ventilation function
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2964-2969. doi:
The Effect of Age on the Macromolecular Permeability of Human Bruch’s Membrane Free
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David J. Moore; Gillian M. Clover
Tags: bruch's basal membrane, permeability, proteins, tissue membrane, donors
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2970-2975. doi:
Heat Shock Protein Hyperexpression on Chorioretinal Layers after Transpupillary Thermotherapy Free
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Thomas Desmettre; Claude-Alain Maurage; Serge Mordon
Tags: heat application, therapeutic, heat-shock proteins, heat-shock proteins 70, lasers, light coagulation
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2976-2980. doi:
Noninvasive Imaging by Optical Coherence Tomography to Monitor Retinal Degeneration in the Mouse Free
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Qiuhong Li; Adrian M. Timmers; Kirk Hunter; Carlos Gonzalez-Pola; Alfred S. Lewin; David H. Reitze; William W. Hauswirth
Tags: diagnostic imaging, mice, optical coherence tomography, retina, retinal degeneration
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2981-2989. doi:
Short-Term Study of Allogeneic Retinal Pigment Epithelium Transplants onto Debrided Bruch’s Membrane Free
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Hao Wang; Debra S. Leonard; Alessandro A. Castellarin; Itsuro Tsukahara; Yoshihiko Ninomiya; Fumihiko Yagi; Noounanong Cheewatrakoolpong; Ilene K. Sugino; Marco A. Zarbin
Tags: adaptive testing, blister, bruch's basal membrane, cats, cell nucleus
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2990-2999. doi:

Retinal Cell Biology

Suppressed Expression of Tubedown-1 in Retinal Neovascularization of Proliferative Diabetic Retinopathy Free
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Robert L. Gendron; William V. Good; Lisa C. Adams; Hélène Paradis
Tags: blood capillaries, endothelial cells, proliferative diabetic retinopathy, retina, retinal neovascularization
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3000-3007. doi:
Effect of GDNF on Neuroblast Proliferation and Photoreceptor Survival: Additive Protection with Docosahexaenoic Acid Free
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Luis E. Politi; Nora P. Rotstein; Néstor G. Carri
Tags: glial cell-line derived neurotrophic factor, photoreceptors, docosahexaenoic acids
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3008-3015. doi:
Mitochondrial Abnormalities in Ageing Macular Photoreceptors Free
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Martin J. Barron; Margaret A. Johnson; Richard M. Andrews; Michael P. Clarke; Philip G. Griffiths; Elizabeth Bristow; Lang-Ping He; Steven Durham; Douglass M. Turnbull
Tags: aging, dna, mitochondrial, mitochondria, photoreceptors, retina
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3016-3022. doi:
Effect of Rpe65 Knockout on Accumulation of Lipofuscin Fluorophores in the Retinal Pigment Epithelium Free
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Martin L. Katz; T. Michael Redmond
Tags: lipofuscin, mice, retinal pigment epithelium
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3023-3030. doi:
Hsp25 and -90 Immunoreactivity in the Normal Rat Eye Free
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Deyrick Osmond Dean; Michael Tytell
Tags: antibodies, body tissue, eye, hsp90 heat-shock proteins, optic nerve
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3031-3040. doi:
Inhibition of RPE Lysosomal and Antioxidant Activity by the Age Pigment Lipofuscin Free
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Farrukh A. Shamsi; Mike Boulton
Tags: antioxidants, lipofuscin, pigment, catalase, retinal pigment cell
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3041-3046. doi:
In Vivo Retinal Gene Expression in Early Diabetes Free
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Antonia M. Joussen; Sui Huang; Vassiliki Poulaki; Kevin Camphausen; Wolf-Dietrich Beecken; Bernd Kirchhof; Anthony P. Adamis
Tags: diabetes mellitus, gene expression, genes, rna
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3047-3057. doi:
Tumorigenicity of the Mixed Spindle-Epithelioid SP6.5 and Epithelioid TP17 Uveal Melanoma Cell Lines Is Differentially Related to α5β1 Integrin Expression Free
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Alain Béliveau; Mélanie Bérubé; Patrick Carrier; Caroline Mercier; Sylvain L. Guérin
Tags: cell lines, integrins, uveal melanoma, neoplasms
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3058-3065. doi:

Visual Neuroscience

Identification of Usher Syndrome Subtypes by ERG Implicit Time Free
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Mathias W. Seeliger; Eberhart Zrenner; Eckart Apfelstedt-Sylla; Gesine B. Jaissle
Tags: electroretinography, usher syndrome
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3066-3071. doi:

Visual Psychophysics and Physiological Optics

Changes in Contrast Sensitivity Induced by Defocus and Their Possible Relations to Emmetropization in the Chicken Free
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Sigrid Diether; Florian Gekeler; Frank Schaeffel
Tags: chickens, contrast sensitivity, lens (device), lens, crystalline, myopia
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 3072-3079. doi:

New Developments in Vision Research

Stem Cells: New Opportunities to Treat Eye Diseases Free
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Iqbal Ahmad
Tags: eye diseases, stem cells, therapeutic uses, embryo, adult
Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2743-2748. doi:

Erratum

Novel Cythochrome P4501B1 (CYP1B1) Gene Mutations in Japanese Patients with Primary Congenital Glaucoma Free
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Investigative Ophthalmology & Visual Science November 2001, Vol.42, 2775. doi:

In-Brief

Genes, Mutations and Gene Therapy Free
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Tags: gene therapy, genes, mutation
Investigative Ophthalmology & Visual Science November 2001, Vol.42, f4-F4. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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