Select a back issue
Select a back issue
  • Alerts
    User Alerts
    You are adding an alert for:
    Investigative Ophthalmology & Visual Science
    You will receive an email whenever new content is published in the Investigative Ophthalmology & Visual Science. You can manage this and all other alerts in My Account
    The alert will be sent to:
    ×
    This feature is available to authenticated users only.
    Sign In or Create an Account ×

Anatomy and Pathology/Oncology

Choroidal Thickness Changes during Altered Eye Growth and Refractive State in a Primate Free
PDF
David Troilo; Debora L. Nickla; Christine F. Wildsoet
Tags: eye, primates, refractive errors, callithrix, choroid
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1249-1258. doi:
Vision-Dependent Changes in the Choroidal Thickness of Macaque Monkeys Free
PDF
Li-Fang Hung; Josh Wallman; Earl L. Smith, III
Tags: cercopithecidae, eye, lens (device), lens, crystalline, refractive errors
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1259-1269. doi:
Conjunctiva-Associated Lymphoid Tissue in the Human Eye Free
PDF
Nadja Knop; Erich Knop
Tags: conjunctiva, eye, lymphoid tissue, lymphocytes, exanthema
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1270-1279. doi:
Evidence for Active Control of Rectus Extraocular Muscle Pulleys Free
PDF
Joseph L. Demer; Sei Yeul Oh; Vadims Poukens
Tags: eye, gaze, magnetic resonance imaging, muscle, muscle of orbit
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1280-1290. doi:

Biochemistry and Molecular Biology

Allelic Variation in the VMD2 Gene in Best Disease and Age-Related Macular Degeneration Free
PDF
Andrew J. Lotery; Francis L. Munier; Gerald A. Fishman; Richard G. Weleber; Samuel G. Jacobson; Louisa M. Affatigato; Brian E. Nichols; Daniel F. Schorderet; Val C. Sheffield; Edwin M. Stone
Tags: age-related macular degeneration, genes, vitelliform dystrophy
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1291-1296. doi:
Altered Expression of Secreted Frizzled-Related Protein-2 in Retinitis Pigmentosa Retinas Free
PDF
Stephen E. Jones; Catherine Jomary; John Grist; Hannah J. Stewart; Michael J. Neal
Tags: proteins, retina, retinitis pigmentosa, sfrp2, rna, messenger
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1297-1301. doi:
BIGH3 Exon 14 Mutations Lead to Intermediate Type I/IIIA of Lattice Corneal Dystrophies Free
PDF
Clair-Florent Schmitt–Bernard; Caroline Guittard; Bernard Arnaud; Jacques Demaille; Angel Argiles; Mireille Claustres; Sylvie Tuffery–Giraud
Tags: exons, family, hereditary corneal dystrophy, mutation, proteins
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1302-1308. doi:

Clinical and Epidemiologic Research

Visual Function and Subjective Quality of Life Compared in Subjects with Acquired Macular Disease Free
PDF
Charlotte A. Hazel; Keziah Latham Petre; Richard A. Armstrong; Mark T. Benson; N. Andrew Frost
Tags: age-related macular degeneration, macular disorders, quality of life, reading (activity), vision
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1309-1315. doi:

Cornea

Detection of Sialomucin Complex (MUC4) in Human Ocular Surface Epithelium and Tear Fluid Free
PDF
Stephen C. Pflugfelder; Zuguo Liu; Dagoberto Monroy; De–Quan Li; Maria E. Carvajal; Shari A. Price–Schiavi; Nebila Idris; Abraham Solomon; Amyee Perez; Kermit L. Carraway
Tags: antibodies, conjunctiva, cornea, epithelium, mucins
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1316-1326. doi:
Modulation of TNF-α–Induced Apoptosis in Corneal Fibroblasts by Transcription Factor NF-κB Free
PDF
Rajiv R. Mohan; Rahul R. Mohan; Woo-Jung Kim; Steven E. Wilson
Tags: apoptosis, cornea, fibroblasts, tumor necrosis factors, transcription factor
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1327-1336. doi:
Role of Cell Adhesion–Associated Protein, Pinin (DRS/memA), in Corneal Epithelial Migration Free
PDF
Yujiang Shi; Mohammadreza Tabesh; Stephen P. Sugrue
Tags: cell adhesion, cornea, corneal epithelium, epithelium, proteins
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1337-1345. doi:
Activation of Epidermal Growth Factor Receptor during Corneal Epithelial Migration Free
PDF
James D. Zieske; Hiroshi Takahashi; Audrey E. K. Hutcheon; Ana C. Dalbone
Tags: cornea, epidermal growth factor receptors, epithelium, wounds and injuries
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1346-1355. doi:
Flow Cytometric Analysis of Inflammatory Markers in Conjunctival Epithelial Cells of Patients with Dry Eyes Free
PDF
Françoise Brignole; Pierre-Jean Pisella; Marie Goldschild; Magda De Saint Jean; Alain Goguel; Christophe Baudouin
Tags: conjunctival epithelial cells, dry eye syndromes, flow cytometry, fluid flow, inflammatory markers
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1356-1363. doi:
Telomerase Activity and p53 Expression in Pterygia Free
PDF
Shigeto Shimmura; Misaki Ishioka; Kazuomi Hanada; Jun Shimazaki; Kazuo Tsubota
Tags: pterygium, telomerase, conjunctiva, protein p53, ultraviolet rays
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1364-1369. doi:

Glaucoma

Experimental Glaucoma and Cell Size, Density, and Number in the Primate Lateral Geniculate Nucleus Free
PDF
Arthur J. Weber; Hao Chen; William C. Hubbard; Paul L. Kaufman
Tags: cell size, glaucoma, lateral geniculate body, neurons, primates
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1370-1379. doi:
Patterns of Intraocular Pressure Elevation after Aqueous Humor Outflow Obstruction in Rats Free
PDF
Lijun Jia; William O. Cepurna; Elaine C. Johnson; John C. Morrison
Tags: aqueous humor, eye, intraocular pressure, rats, optic nerve
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1380-1385. doi:
Truncations in the TIGR Gene in Individuals with and without Primary Open-Angle Glaucoma Free
PDF
Dennis S. C. Lam; Yuk Fai Leung; John K. H. Chua; Larry Baum; Dorothy S. P. Fan; Kwong Wai Choy; Chi Pui Pang
Tags: genes, myoc gene, open-angle glaucoma, glaucoma
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1386-1391. doi:

Immunology and Microbiology

Herpes Simplex Virus–Mediated Gene Delivery to the Rodent Visual System Free
PDF
Brian Spencer; Seema Agarwala; Michael Miskulin; Morton Smith; Curtis R. Brandt
Tags: genes, transgenes, viruses, visual system, simplexvirus
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1392-1401. doi:
Role of Macrophages in Restricting Herpes Simplex Virus Type 1 Growth after Ocular Infection Free
PDF
Hao Cheng; Terrence M. Tumpey; Herman F. Staats; Nico van Rooijen; John E. Oakes; Robert N. Lausch
Tags: eye infections, human herpesvirus 1, infections, macrophages, viruses
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1402-1409. doi:
Analysis of In Vivo Regulatory Properties of T Cells Activated In Vitro by TGFβ2-Treated Antigen Presenting Cells Free
PDF
Takeshi Kezuka; J. Wayne Streilein
Tags: atrial premature complexes, t-lymphocytes, ovum, mice
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1410-1421. doi:
Langerhans Cells, Orthotopic Corneal Allografts, and Direct and Indirect Pathways of T-Cell Allorecognition Free
PDF
Yoichiro Sano; Bruce R. Ksander; J. Wayne Streilein
Tags: allografting, cornea, langerhans cell, t-lymphocytes, donors
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1422-1431. doi:
Lysostaphin Treatment of Methicillin-Resistant Staphylococcus aureus Keratitis in the Rabbit Free
PDF
Joseph J. Dajcs; Emma B. H. Hume; Judy M. Moreau; Armando R. Caballero; Bennetta M. Cannon; Richard J. O’Callaghan
Tags: keratitis, lysostaphin, methicillin-resistant staphylococcus aureus, oryctolagus cuniculus, cornea
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1432-1437. doi:
PCR-RFLP–Mediated Detection and Speciation of Bacterial Species Causing Endophthalmitis Free
PDF
Narciss Okhravi; Peter Adamson; Melville M. Matheson; Hamish M. A. Towler; Susan Lightman
Tags: polymerase chain reaction, endophthalmitis, restriction fragment length polymorphism, dna
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1438-1447. doi:
Synergistic Induction of Eotaxin Expression in Human Keratocytes by TNF-α and IL-4 or IL-13 Free
PDF
Naoki Kumagai; Ken Fukuda; Yoshitsugu Ishimura; Teruo Nishida
Tags: interleukin-13, interleukin-4, keratocytes, tumor necrosis factors, rna, messenger
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1448-1453. doi:

Lens

Age-Related Changes in the Absorption Characteristics of the Primate Lens Free
PDF
Elizabeth R. Gaillard; Lei Zheng; John C. Merriam; James Dillon
Tags: lens (device), lens, crystalline, primates, process of absorption
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1454-1459. doi:
Contribution of Calpain Lp82–Induced Proteolysis to Experimental Cataractogenesis in Mice Free
PDF
Yoshikuni Nakamura; Chiho Fukiage; Marjorie Shih; Hong Ma; Larry L. David; Mitsuyoshi Azuma; Thomas R. Shearer
Tags: calpain, cataract, lens (device), lens, crystalline, mice
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1460-1466. doi:
Overexpression of Na+-Dependent Myo-inositol Transporter Gene in Mouse Lens Led to Congenital Cataract Free
PDF
Zhirong Jiang; Sookja K. Chung; Cheng Zhou; Patrick R. Cammarata; Stephen S. M. Chung
Tags: cataract, congenital cataract, inositol, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1467-1472. doi:
Transition Metal–Catalyzed Oxidation of Ascorbate in Human Cataract Extracts: Possible Role of Advanced Glycation End Products Free
PDF
Poonam Saxena; Amit K. Saxena; Xiao–Lan Cui; Mark Obrenovich; Krishna Gudipaty; Vincent M. Monnier
Tags: copper, crystallins, lens, crystalline, oxidation, lens (device)
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1473-1481. doi:

Retina

Erythrocyte Sodium–Lithium Countertransport and Proliferative Diabetic Retinopathy Free
PDF
Jacqueline M. Lopes de Faria; Lilia A. Silveira; Marcelo Morgano; Elizabete J. Pavin; José B. Lopes de Faria
Tags: erythrocytes, lithium, proliferative diabetic retinopathy, sodium, diabetes mellitus, type 1
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1482-1485. doi:
Intersession Repeatability of Macular Thickness Measurements with the Humphrey 2000 OCT Free
PDF
Dara Koozekanani; Cynthia Roberts; Steven E. Katz; Ed E. Herderick
Tags: eye, fovea centralis, pupil, refractive errors, software
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1486-1491. doi:
Macular Pigment Optical Density in a Southwestern Sample Free
PDF
Billy R. Hammond, Jr.; Mary Caruso–Avery
Tags: optics, pigment
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1492-1497. doi:
Retinal Sensitivity to Flicker Modulation: Reduced by Early Age-Related Maculopathy Free
PDF
Benedetto Falsini; Antonello Fadda; Giancarlo Iarossi; Marco Piccardi; Doriana Canu; Angelo Minnella; Sebastiano Serrao; Luigi Scullica
Tags: age-related macular degeneration, photopsia
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1498-1506. doi:
Squalamine Improves Retinal Neovascularization Free
PDF
Rosemary D. Higgins; Raymond J. Sanders; Yun Yan; Michael Zasloff; Jon I. Williams
Tags: mice, neovascularization, pathologic, oxygen, retinal diseases, retinal neovascularization
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1507-1512. doi:
Dose Dependency of Canthaxanthin Crystals in Monkey Retina and Spatial Distribution of its Metabolites Free
PDF
Regina Goralczyk; Felix M. Barker; Susanne Buser; Hans Liechti; Jochen Bausch
Tags: canthaxanthin, retina, crystal structure, cercopithecidae, metabolites
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1513-1522. doi:
Intravitreal Toxicology and Duration of Efficacy of a Novel Antiviral Lipid Prodrug of Ganciclovir in Liposome Formulation Free
PDF
Lingyun Cheng; Karl Y. Hostetler; Sunan Chaidhawangul; Michael F. Gardner; James R. Beadle; Kelly S. Keefe; Germaine Bergeron–Lynn; Gregory M. Severson; Kelly A. Soules; Arthur J. Mueller; William R. Freeman
Tags: antiviral agents, eye, ganciclovir, human herpesvirus 1, lipids
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1523-1532. doi:

Retinal Cell Biology

Differential Expression of Neuroendocrine-Specific Protein in Form-Deprived Chick Eyes Free
PDF
Shigeki Fujii; Michael F. T. Escaño; Kazuki Ishibashi; Motoko Fujii; Yoshibumi Sekiya; Misao Yamamoto; Kiyofumi Saijoh
Tags: body tissue, differential display technique, eye, myopia, neurosecretory systems
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1533-1541. doi:
Müller Cell Outgrowth after Retinal Detachment: Association with Cone Photoreceptors Free
PDF
Geoffrey P. Lewis; Steven K. Fisher
Tags: retinal cone, retinal detachment
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1542-1545. doi:
Characterization of Rhodopsin Mis-sorting and Constitutive Activation in a Transgenic Rat Model of Retinitis Pigmentosa Free
PDF
Eric S. Green; Michael D. Menz; Matthew M. LaVail; John G. Flannery
Tags: animals, transgenic, retinitis pigmentosa, rhodopsin, rats, proteins
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1546-1553. doi:
Glucose-Specific Regulation of Aldose Reductase in Human Retinal Pigment Epithelial Cells In Vitro Free
PDF
Douglas N. Henry; Robert N. Frank; Seth R. Hootman; Sandra E. Rood; Charles W. Heilig; Julia V. Busik
Tags: glucose, retinal pigment cell, aldehyde reductase, proteins, rna, messenger
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1554-1560. doi:
Quantitative MR Imaging Study of Intravitreal Sustained Release of VEGF in Rabbits Free
PDF
Nadir Alikacem; Toyohisa Yoshizawa; Kevin D. Nelson; Charles A. Wilson
Tags: magnetic resonance imaging, oryctolagus cuniculus, vascular endothelial growth factor a, eye, vitreous body
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1561-1569. doi:

Visual Neuroscience

An Attempt to Detect Glaucomatous Damage to the Inner Retina with the Multifocal ERG Free
PDF
Donald C. Hood; Vivienne C. Greenstein; Karen Holopigian; Rebecca Bauer; Bahar Firoz; Jeffrey M. Liebmann; Jeffrey G. Odel; Robert Ritch
Tags: electroretinography, erg protein, human, glaucoma, retina, visual fields
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1570-1579. doi:
An Interocular Comparison of the Multifocal VEP: A Possible Technique for Detecting Local Damage to the Optic Nerve Free
PDF
Donald C. Hood; Xian Zhang; Vivienne C. Greenstein; Shreya Kangovi; Jeffrey G. Odel; Jeffrey M. Liebmann; Robert Ritch
Tags: evoked potentials, visual, eye, optic nerve, visual fields
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1580-1587. doi:
The Development of Scotopic Sensitivity Free
PDF
Anne B. Fulton; Ronald M. Hansen
Tags: adult, electroretinography, infant, rod photoreceptors, parafoveal region
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1588-1596. doi:
Waveform Changes of the First-Order Multifocal Electroretinogram in Patients with Glaucoma Free
PDF
Shigeru Hasegawa; Mineo Takagi; Tomoaki Usui; Ritsuko Takada; Haruki Abe
Tags: electroretinography, erg protein, human, glaucoma, waveforms
Investigative Ophthalmology & Visual Science May 2000, Vol.41, 1597-1603. doi:

In-Brief

Old Theories and New Ideas on Ocular Function Free
PDF
Tags: cataract, conjunctiva, copper, eye, fibrosis
Investigative Ophthalmology & Visual Science May 2000, Vol.41, f3-F4. doi:
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept